APOBEC2
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Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
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Overview
Probable C->U-editing enzyme APOBEC-2 is a protein that in humans is encoded by the APOBEC2 gene. -
Synonyms
APOBEC2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2; probable C-> U-editing enzyme APOBEC-2; ARCD1; ARP1; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 2; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 2; MGC128604; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- APOBEC2 Related Articles
APOBEC2 involved in several pathways and played different roles in them. We selected most pathways APOBEC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOBEC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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APOBEC2 has several biochemical functions, for example, RNA binding, cytidine deaminase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOBEC2 itself. We selected most functions APOBEC2 had, and list some proteins which have the same functions with APOBEC2. You can find most of the proteins on our site.
Function | Related Protein |
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RNA binding | NPM1;DAZ4;PPP1R8;BOLL;SUZ12;SMN1;PATL2;RBM12B1;SNRPF |
cytidine deaminase activity | APOBEC1;APOBEC2;CDA;APOBEC3F;WBP2NL;APOBEC3G;AICDA;APOBEC3H |
zinc ion binding | TRIM35-31;LNPEP;MARCH7;NSMCE2;PHC2A;ABLIM1B;Shh;TRIM68;ESR1 |
APOBEC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOBEC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOBEC2.
- Q&As
- Reviews
Q&As (18)
Ask a questionDue to limited understanding of APOBEC2's function and its relevance to diseases, there are currently no known specific drugs or inhibitors that target APOBEC2 protein. Further research is necessary to elucidate its role and potential therapeutic targets, if any.
The impact of APOBEC2 protein on RNA stability or degradation has not been widely investigated. However, some research suggests that APOBEC2 may interact with proteins involved in RNA decay pathways, indicating its potential role in modulating RNA stability. Further studies are needed to elucidate the precise mechanisms and extent of APOBEC2's involvement in RNA stability or degradation processes.
The interacting partners of APOBEC2 protein are not extensively characterized. However, it has been reported to interact with APOBEC1 and potentially modulate its editing activity. Additionally, it may interact with other proteins involved in RNA metabolism, leading to potential functional implications for APOBEC2 in RNA processing.
The ability of APOBEC2 to edit its own mRNA has not been extensively studied. However, there is evidence suggesting that APOBEC2 may undergo self-editing, similar to other members of the APOBEC family. Further research is needed to determine the extent and significance of self-editing by APOBEC2.
While the primary function of APOBEC2 is not well established, studies suggest that it may have non-editing functions. It has been implicated in processes like myogenesis and muscle development. APOBEC2 may be involved in regulating gene expression or protein interactions beyond its editing activity.
The involvement of APOBEC2 protein in viral defense or immune response is not well established. While other APOBEC family members, such as APOBEC3 proteins, are known to have antiviral activity, APOBEC2's potential role in this context is still largely unexplored. Further studies are needed to determine if APOBEC2 contributes to viral defense mechanisms or immune response pathways.
The therapeutic targeting of APOBEC2 protein has not been extensively explored. However, given its potential involvement in cellular processes and diseases, it might serve as a target for therapeutic interventions in the future. Developing specific inhibitors or modulators of APOBEC2 activity could be a potential avenue of research for therapeutic purposes.
While APOBEC1 is known to regulate lipid metabolism through its editing activity on APOB mRNA, the role of APOBEC2 in lipid metabolism is not well characterized. Further studies are required to determine if APOBEC2 has any direct impact on lipid metabolism or if its functions are mainly related to other cellular processes.
The role of APOBEC2 protein in embryonic development is not fully understood. Studies in mice have shown that APOBEC2 is expressed during early embryogenesis in various tissues. However, further research is required to determine if APOBEC2 plays a crucial role in embryonic development, and if its absence results in any notable developmental abnormalities.
APOBEC2 protein exhibits tissue-specific expression patterns. It is found in various tissues, including skeletal muscle, heart, and brain. However, the exact distribution and levels of APOBEC2 expression in different tissues are not fully characterized.
The regulation of APOBEC2 expression is not fully understood. It is known that APOBEC2 expression is regulated by various genetic and epigenetic factors. For instance, certain transcription factors and signaling pathways may influence APOBEC2 expression levels. However, more studies are required to unravel the precise mechanisms of APOBEC2 regulation.
The regulatory mechanisms controlling APOBEC2 protein activity remain largely unknown. It is still unclear if APOBEC2 undergoes post-translational modifications or if it requires specific cofactors for its activity. More research is needed to identify the regulatory mechanisms that govern APOBEC2 protein function and activity.
Currently, there are no validated diagnostic or prognostic applications of APOBEC2 protein. However, as more knowledge about its functions and associations with diseases is acquired, there is potential for APOBEC2 to be explored as a biomarker in certain diseases. Future research may shed light on its diagnostic or prognostic relevance in specific contexts.
The association of APOBEC2 protein with diseases is currently unclear. Unlike other members of the APOBEC family, APOBEC2 has not been extensively studied in the context of disease pathogenesis. More research is needed to determine if APOBEC2 plays a significant role in any specific disease processes.
Currently, there are no well-established disease-causing mutations identified in the APOBEC2 gene. However, genetic variations in APOBEC2 have been studied in relation to certain conditions, such as obesity and muscle-related disorders. Further research is needed to understand the potential implications of these genetic variations on disease susceptibility or pathogenesis.
The potential of APOBEC2 protein as a drug target has not been extensively investigated. As our understanding of its role and involvement in diseases expands, it may be explored as a target for therapeutic development. However, significant research is required to determine the feasibility and efficacy of targeting APOBEC2 for therapeutic purposes.
The involvement of APOBEC2 protein in cancer is not well understood. However, several other members of the APOBEC family, like APOBEC3 proteins, have been implicated in cancer due to their ability to mutate DNA. It remains to be determined if APOBEC2 has similar implications in cancer biology, and further studies are required to explore its role, if any, in cancer development or progression.
The factors influencing APOBEC2 expression or activity are not well characterized. It is likely that both genetic and environmental factors can influence APOBEC2 levels or its functional activity. Further research is needed to identify the specific factors that modulate APOBEC2 expression or activity and understand their impact on physiological processes or disease outcomes.
Customer Reviews (4)
Write a reviewThe reliable and high-quality results obtained using APOBEC2 protein make it an excellent choice for researchers studying protein structures.
This enhanced visibility and distinctness of the protein bands greatly aided in the accurate analysis and interpretation of my Western Blotting results.
Its reliability, versatility, and ability to deliver clear and reliable results make it a top choice for researchers in need of a high-quality protein for their experiments.
APOBEC2 protein has exhibited remarkable performance in Western Blotting experiments.
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