ARL4A
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Official Full Name
ADP-ribosylation factor-like 4A
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Overview
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. -
Synonyms
ARL4A; ADP-ribosylation factor-like 4A; ADP ribosylation factor like 4 , ARL4; ADP-ribosylation factor-like protein 4A; ADP-ribosylation factor-like 4; ARL4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- E.Coli or Yeast
- HEK293
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
ARL4A involved in several pathways and played different roles in them. We selected most pathways ARL4A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ARL4A has several biochemical functions, for example, GTP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL4A itself. We selected most functions ARL4A had, and list some proteins which have the same functions with ARL4A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | ACSM1;GSPT2;CDC42L2;ARFIP2;RAB27A;RAB7L1;TUBD1;RHEB;NUDT16 |
| protein binding | RAB11A;CEACAM21;CKM;TRP53;PMEPA1;RAB8A;GNG5;CRY1A;SCARA3 |
ARL4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL4A here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL4A.
CCDC102B; GOLGA2; CCDC57; SPATC1L; q7cjh7_yerpe
- Q&As
- Reviews
Q&As (6)
Ask a questionMutations in the ARL4A gene have not been extensively studied. However, some studies have suggested its potential involvement in cancer progression and metastasis. Further research is required to fully understand any disease associations or potential therapeutic implications.
Dysregulation of ARL4A expression has been implicated in various pathological conditions. Alterations in its expression levels or activity may contribute to abnormalities in vesicular trafficking, cytoskeletal organization, and overall cellular homeostasis.
Yes, ARL4A interacts with several proteins to regulate various cellular processes. It can interact with GTPase-activating proteins (GAPs), guanine nucleotide exchange factors (GEFs), and effector proteins involved in vesicle trafficking and cytoskeletal dynamics.
ARL4A itself is not considered a signaling molecule in canonical signaling pathways. However, it may modulate the activity of certain signaling molecules by regulating their intracellular transport or localization.
ARL4A is generally expressed in a wide range of tissues and cell types, indicating its ubiquitous nature. Its expression may vary in different tissues and developmental stages.
The therapeutic potential of targeting ARL4A is currently being explored. Its involvement in cellular processes and potential role in diseases make it a potential therapeutic target. However, further research is needed to fully understand its mechanisms and implications for targeted therapeutics.
Customer Reviews (8)
Write a reviewThe versatility of the ARL4A protein makes it a valuable asset in my research.
The ARL4A protein is renowned for its exceptional quality, making it a perfect match for my experimental requirements.
the ARL4A protein exhibits superior performance across a range of experimental applications.
In addition to its high-quality attributes, the manufacturer of the ARL4A protein offers exemplary technical support.
Its superior purity and stability ensure reliable and accurate results, instilling confidence in my research.
Whether I am studying protein interactions, cellular localization, or signaling pathways, the ARL4A protein consistently delivers reliable and reproducible data, enabling significant scientific advancements.
Its versatility allows for its successful implementation in diverse areas such as molecular biology, cellular assays, and protein-protein interactions.
Their assistance has been invaluable in streamlining my experiments and overcoming obstacles effectively.
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