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ASPA

  • Official Full Name

    aspartoacylase

  • Overview

    This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate.;NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein;is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript;variants have been found for this gene.
  • Synonyms

    ASPA; aspartoacylase; aspartoacylase (aminoacylase 2, Canavan disease); ACY2; aminoacylase 2; ASP; Canavan disease; ACY 2; ACY-2; ACY2_HUMAN; Aminoacylase-2; Aminoacylase2; Aspartoacylase (Canavan disease); NUR 7; NUR7; OTTMUSP00000006437; RP23-213I10.1; Small lethargic; OTTHUMP00000115814;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bacillus subtilis
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli or Yeast
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • His|Myc
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ASPA-163H Recombinant Human ASPA protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ASPA-873H Recombinant Human ASPA Mammalian Cell His
Human ASPA-916H Recombinant Human ASPA protein, GST-tagged Wheat Germ GST
Human ASPA-1920H Recombinant Human Aspartoacylase, His-tagged His
Human ASPA-162H Recombinant Human ASPA protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ASPA-8647HCL Recombinant Human ASPA 293 Cell Lysate HEK293 N/A
Human ASPA-2438H Recombinant Human ASPA Protein (1-313 aa), His-Myc-tagged Yeast His/Myc 1-313 aa
Human ASPA-422H Recombinant Human ASPA Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human ASPA-4991H Recombinant Human ASPA protein, His&Myc-tagged HEK293 His&Myc 1-313aa
Human ASPA-1056HF Recombinant Full Length Human ASPA Protein, GST-tagged In Vitro Cell Free System GST 313 amino acids
Human ASPA-2560H Recombinant Human ASPA protein, His&Myc-tagged E.coli His&Myc 1-313aa
Human ASPA-1936H Recombinant Human ASPA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ASPA-2507H Recombinant Human ASPA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ASPA-2202H Recombinant Human ASPA protein, His&Myc-tagged Insect Cell His&Myc 1-313aa
Human ASPA-2507H-B Recombinant Human ASPA Protein Pre-coupled Magnetic Beads HEK293
Human ASPA-252H Recombinant Human ASPA Protein, His-tagged E.coli N-His Met1-Ile243
Mouse Aspa-531M Recombinant Mouse Aspa Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Aspa-253M Recombinant Mouse Aspa Protein, His-tagged E.coli N-His Tyr63-His312
Rat ASPA-829R Recombinant Rat ASPA Protein Mammalian Cell His
Rat ASPA-485R-B Recombinant Rat ASPA Protein Pre-coupled Magnetic Beads HEK293
Rat ASPA-485R Recombinant Rat ASPA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bacillus subtilis ASPA-1339B Recombinant Bacillus subtilis ASPA protein, His-tagged E. coli or Yeast His
Cynomolgus Monkey ASPA-317C Recombinant Cynomolgus ASPA Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey ASPA-67C Recombinant Cynomolgus Monkey ASPA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey ASPA-67C-B Recombinant Cynomolgus Monkey ASPA Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ASPA-430R Recombinant Rhesus monkey ASPA Protein, His-tagged Mammalian Cell His
Rhesus Macaque ASPA-259R Recombinant Rhesus Macaque ASPA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ASPA-259R-B Recombinant Rhesus Macaque ASPA Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ASPA-6102Z Recombinant Zebrafish ASPA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ASPA Related Articles

ASPA involved in several pathways and played different roles in them. We selected most pathways ASPA participated on our site, such as Alanine, aspartate and glutamate metabolism, Histidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASPA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Alanine, aspartate and glutamate metabolismGOT1;ASPA;GOT2A;GLULC;ALDH4A1;GLUD1;ABAT;GLS;AGXT
Histidine metabolismALDH2;ALDH3A2A;ALDH9A1;CARNS1;ALDH9A1B;CNDP2;HNMT;ALDH1B1;HDC
Metabolic pathwaysCYP2U1;PPAP2D;PLA2G4AA;ATP6AP1B;DHRS3;CKMA;MDH1AA;PI4K2A;SAT2

ASPA has several biochemical functions, for example, aminoacylase activity, aspartoacylase activity, hydrolase activity, acting on ester bonds. Some of the functions are cooperated with other proteins, some of the functions could acted by ASPA itself. We selected most functions ASPA had, and list some proteins which have the same functions with ASPA. You can find most of the proteins on our site.

Function Related Protein
aminoacylase activityCAT;ACY1;ASPA;ACY3;DARS
aspartoacylase activity
hydrolase activity, acting on ester bondsPTER;ENDOU2;LIPN;ESD;APMAP;ACY3.2;LIPM;C11orf54;ASPA
metal ion bindingOSR1;CYP2K6;ZNFL1;CYP2D10;TGM4;PPM1L;PPARAA;ZFP458;NAIP7
protein bindingMATN3;ZNF133;LTBR;FBXO5;GNMT;GEMIN6;BEX2;DRD3;MEF2A

ASPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASPA here. Most of them are supplied by our site. Hope this information will be useful for your research of ASPA.

ACY3

Chang, Z; Lu, M; et al. Production of disulfide bond-rich peptides by fusion expression using small transmembrane proteins of Escherichia coli. AMINO ACIDS 47:579-587(2015).
Abad, FX; Busquets, N; et al. Serological and virological surveys of the influenza A viruses in Antarctic and sub-Antarctic penguins. ANTARCTIC SCIENCE 25:339-344(2013).
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01/02/2021

    This brand of protein reagent has consistently been my unwavering choice, consistently providing me with utmost satisfaction.

    06/02/2020

      The reliability and dependability of this brand of protein substance make it an indispensable partner in my research endeavors.

      01/26/2019

        The utilization of this protein substance has resulted in even more reliable and accurately interpreted experimental results, leaving me completely satisfied.

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