ATP9A
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Official Full Name
ATPase, class II, type 9A
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Synonyms
ATP9A; ATPase, class II, type 9A; probable phospholipid-transporting ATPase IIA; ATPIIA; KIAA0611; ATP 9A; ATPase class II type 9A; ATPase IIA; ATPase type IV phospholipid transporting (P type); ATPase type IV phospholipid transporting (P type)(putative); Phospholipid transporting ATPase IIA; Probable phospholipid transporting ATPase IIA; OTTHUMP00000043369; OTTHUMP00000043371; phospholipid-transporting ATPase IIA; ATPase type IV, phospholipid-transporting (P-type),(putative);
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | ATP9A-1018H | Recombinant Human ATP9A protein, GST-tagged | Wheat Germ | GST |
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| Human | ATP9A-1098HF | Recombinant Full Length Human ATP9A Protein, GST-tagged | In Vitro Cell Free System | GST | 1047 amino acids |
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| Mouse | ATP9A-2180M | Recombinant Mouse ATP9A Protein | Mammalian Cell | His |
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| Mouse | ATP9A-890M-B | Recombinant Mouse ATP9A Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | ATP9A-890M | Recombinant Mouse ATP9A Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ATP9A Related Articles
ATP9A involved in several pathways and played different roles in them. We selected most pathways ATP9A participated on our site, such as XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP9A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | DDN;MICALL2;TENC1;LIMS2;SNTB1;CLNK;CMIP;GAB3;FLII |
ATP9A has several biochemical functions, for example, ATP binding, hydrolase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP9A itself. We selected most functions ATP9A had, and list some proteins which have the same functions with ATP9A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | RIPK4;P2RX3;ATP2A2;MOCS3;BMP2K;CDK9;JAK1;MERTK;SRX1 |
| hydrolase activity | NOTUM1A;CNOT6;HE1A;MOV10B.1;ATP11A;PEO1;PTPRZ1;UNGA;ADAMTS16 |
| magnesium ion binding | MAP3K6;PKLR;ENO2;PPM1AB;ENOPH1;ATP11A;ENO1B;LHPP;NT5C1AA |
| metal ion binding | GTF3AA;ZFP287;GALNT7;GALNT4;TRIM67;CYP51;TNNI3;FTH1B;TRMT1L |
| nucleotide binding | MYO6A;HNRNPC;AKAP17A;KDRL;SNRPB2;MSI1;RIPK4;DPYDB;TIAL1 |
| phospholipid-translocating ATPase activity | Atp8a2;ATP11A;ATP8B3;ATP10A;ATP8B5;ATP9A;ATP9B;ATP8A1;ATP11C |
ATP9A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP9A here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP9A.
- Q&As
- Reviews
Q&As (6)
Ask a questionATP9A gene is widely expressed in various human tissues. However, its expression levels may vary in different tissues and cell types.
Detection of ATP9A gene mutations is usually performed by gene sequencing technology. Common methods include Sanger sequencing, next generation sequencing (NGS), etc. These methods can detect point mutations, insertion/deletion mutations and so on on ATP9A gene.
The protein is involved in the phospholipid turnover process of cell membrane and maintains the stability of cell membrane. ATP9A gene mutation may lead to abnormal protein function, and then affect the stability of cell membrane.
Currently, there is no specific therapy targeting ATP9A gene mutations. However, understanding the mutation status of ATP9A gene can help doctors better understand the disease risk and prognosis of patients to develop individualized treatment plans.
This gene mutation may lead to the structural and functional abnormalities of ATP9A protein, affecting the phospholipid turnover process of the inner and outer membranes of cells. This may negatively affect the function and stability of the cells.
The effects of specific ATP9A gene mutations on nervous system development are unknown. However, several studies have shown that ATP9A protein plays an important role in nerve cells, and mutations may be associated with intellectual disability and neurodevelopmental abnormalities.
Customer Reviews (3)
Write a reviewThe stability of ATP9A is very stable under a variety of environmental conditions, whether it is low temperature, high temperature, or other extreme environments, and its performance remains consistent.
As the production process of ATP9A adopts the most advanced biotechnology, the production process is more green and sustainable.
Due to the short half-life and high clearance rate of recombinant proteins, their rapid clearance from the body reduces the risk of side effects.
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