ATRN
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Official Full Name
attractin
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Overview
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. -
Synonyms
ATRN; attractin; DPPT L; mahogany protein; MGCA; attractin-2; mahogany homolog; DPPT-L; KIAA0548; MGC126754;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- CHO
- E.coli
- E.Coli or Yeast
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N
- Involved Pathway
- Protein Function
- Interacting Protein
ATRN involved in several pathways and played different roles in them. We selected most pathways ATRN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ATRN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ATRN has several biochemical functions, for example, carbohydrate binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATRN itself. We selected most functions ATRN had, and list some proteins which have the same functions with ATRN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | BCAN;Cd209g;CLEC1A;REG3B;PRG3;SELL;REG3G;KLRB1B;ILLR4 |
| receptor activity | P2RY1;SIGLEC7;KLRB1B;NOTCH4;CHRM3;PAQR5;GUCY1A3;ADIPOR1A;NLGN2A |
ATRN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATRN here. Most of them are supplied by our site. Hope this information will be useful for your research of ATRN.
mutT7; rbsB5; rph; nadB; gntK; COPS5
- Q&As
- Reviews
Q&As (6)
Ask a questionATRN gene mutations may lead to hereditary hemorrhagic telangiectasia and other diseases. The main features of the disease include telangiectasia on the skin and mucosa, epistaxis, and bleeding in internal organs.
Yes, the ATRN gene may interact with other genes involved in the regulation of cell development and function, such as the Netrin-1 gene in nervous system development. These interactions may affect the function and regulatory network of ATRN genes.
Yes, ATRN gene expression is affected by a variety of regulatory factors, including binding of transcription factors, activation of signaling pathways, etc. These regulatory mechanisms ensure the adaptability and stability of the ATRN gene.
At present, no direct association between ATRN gene and cancer has been found. However, the regulatory role of ATRN genes in cell proliferation and differentiation may be indirectly related to tumorigenesis and progression.
The ATRN gene is widely expressed in the human body, but its expression level may vary in different tissues and organs. Its expression is higher in brain, retina, kidney and other tissues.
The research on ATRN gene mainly focuses on the analysis of its structure and function, the exploration of its regulatory mechanism, and the relationship with genetic diseases. So far, several important findings have been made regarding the function and regulation of ATRN genes.
Customer Reviews (3)
Write a reviewATRN's exceptional purity ensures accurate and reproducible experimental results.
The protein manufacturer's products are backed by strong scientific research and development to provide customers with cutting-edge solutions.
Because ATRN is resistant to degradation and its stability under various experimental conditions makes it the best choice for Western blot analysis.
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