Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

B3GNT5

Official Full Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Overview

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.
Synonyms

B3GNT5; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; B3GN T5; beta3Gn T5; B3GN-T5; Beta 1,3 N acetyglucosaminyltransferase Lc3 synthase; Beta 1,3 N acetylglucosaminyltransferase 5; Beta 1,3-N acetylglucosaminyltransferase bGnT5; Beta-1,3-Gn-T5; Beta3Gn-T5; beta3GnT5; BGnT-5; EC 2.4.1.-; Lactotriaosylceramide synthase; Lc(3)Cer synthase; Lc3 synthase; UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 5; OTTHUMP00000212932; beta-1,3-N-acetylglucosaminyltransferase 5; beta-1,3-N-acetylglucosaminyltransferase bGnT-5; beta 1,3 N-acetyglucosaminyltransferase Lc3 synthase;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	B3GNT5-023H	Recombinant Human B3GNT5 protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	B3GNT5-10106H	Recombinant Human B3GNT5, His-tagged	E.coli	His	C-term-343a.a.	$319 / 25ug
Human	B3GNT5-8542HCL	Recombinant Human B3GNT5 293 Cell Lysate	HEK293	N/A		Inquiry
Human	B3GNT5-1634HF	Recombinant Full Length Human B3GNT5 Protein, GST-tagged	In Vitro Cell Free System	GST	378 amino acids	Inquiry
Mouse	B3GNT5-2243M	Recombinant Mouse B3GNT5 Protein	Mammalian Cell	His		Inquiry
Mouse	B3GNT5-932M	Recombinant Mouse B3GNT5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	B3GNT5-932M-B	Recombinant Mouse B3GNT5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	B3GNT5-917R	Recombinant Rat B3GNT5 Protein	Mammalian Cell	His		Inquiry
Rat	B3GNT5-575R	Recombinant Rat B3GNT5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	B3GNT5-575R-B	Recombinant Rat B3GNT5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	B3GNT5-3813C	Recombinant Chicken B3GNT5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

B3GNT5 involved in several pathways and played different roles in them. We selected most pathways B3GNT5 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GNT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosphingolipid biosynthesis - lacto and neolacto series	FUT2;B3GNT3;B3GNT1;B3GNT2;B3GALT5;FUT6;ABO;B4GALT1;B3GNT5A
Metabolic pathways	FUT1;POLE2;CKBB;MGAT1B;ATIC;HYKK;EXTL1;PCCA;GLUD2

B3GNT5 has several biochemical functions, for example, beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity, galactosyltransferase activity, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GNT5 itself. We selected most functions B3GNT5 had, and list some proteins which have the same functions with B3GNT5. You can find most of the proteins on our site.

Function	Related Protein
beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity
galactosyltransferase activity	B3GALT6;B4GALT1;B3GNT9-PS;B3GNT2B;GTDC2;B3GNT5B;B4GALT3;GALNTL4;POMGNT2
lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity	B3GNT5A;B3GNT5;B3GNT5B

B3GNT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GNT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GNT5.

CBX7