BAZ1B
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Official Full Name
bromodomain adjacent to zinc finger domain, 1B
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Overview
The human WSTF gene is located within the common Williams Syndrome (WS) deletion area at chromosome 7q11.23. Several WSTF gene products have been detected with little difference in length of polypeptides. Functional motifs identified by sequence-homology -
Synonyms
BAZ1B; bromodomain adjacent to zinc finger domain, 1B; WBSCR9, WBSCR10; tyrosine-protein kinase BAZ1B; transcription factor WSTF; Williams Beuren syndrome chromosome region 9; Williams Beuren syndrome chromosome region 10; WSTF; hWALp2; williams syndrome;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- GST|His|Strep
- His
- His (Fc)
- Avi
- His|Flag
- His|Strep
- Involved Pathway
- Protein Function
- Interacting Protein
- BAZ1B Related Articles
- BAZ1B Related Research Area
BAZ1B involved in several pathways and played different roles in them. We selected most pathways BAZ1B participated on our site, such as DNA Double Strand Break Response, DNA Double-Strand Break Repair, DNA Repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with BAZ1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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DNA Double Strand Break Response | UBE2V2;BAZ1B;BRE;CHEK2;FAM175A;KDM4B;EYA3;RAD50;UIMC1 |
DNA Double-Strand Break Repair | BRE;PPP4R2A;THRSP;PPP4R2B;PAXIP1;SMARCA5;CHEK2;PPP4CA;UIMC1 |
DNA Repair | EYA4;UBE2V2;TDP2;CHEK1;DDB1;UIMC1;COPS8;EYA3;FUZ |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | EYA3;EYA2;KDM4B;KDM4A;EYA4;BAZ1B |
BAZ1B has several biochemical functions, for example, ATP binding, chromatin binding, histone kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BAZ1B itself. We selected most functions BAZ1B had, and list some proteins which have the same functions with BAZ1B. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | PLK4;TTF2;MAPK8B;ACTB;KARS;MAP4K6;PDPK1;ASCC3;UBE2KA |
chromatin binding | PHC1;NCOA2;EP300;NEUROD1;NOC3L;MED1;NUPR1;POLE;AIRE |
histone kinase activity | CCNB1;BAZ1B;CDK1 |
lysine-acetylated histone binding | ATAD2B;PSME4B;BAZ1B;BRD9;MLL1;TAF1;TRIM24;BRD7;BRD2 |
non-membrane spanning protein tyrosine kinase activity | JAK1;PTK2AB;TNK2B;LYN;DYRK1A;TEC;Fert2;YES1;WEE2 |
protein binding | MST1;SSX5;RPL37A;LRR1;GLS2;Apba1;ICAM4;SPSB3;STAM2 |
protein tyrosine kinase activity | EPHB4A;EPHA4B;PTK7;EPHA7;MAP2K1;CSK;FYNB;BTK;FGFR1A |
vitamin D receptor activator activity | |
zinc ion binding | RNF24;KCMF1;MTF2;NR1D2B;LMO4B;TRAF4;ADAM33;ADAM10;PRKCBP1L |
BAZ1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BAZ1B here. Most of them are supplied by our site. Hope this information will be useful for your research of BAZ1B.
SMARCA5; MYH1; NR4A2; Smarca5; BAZ1A; BAZ2A; PHLDA3; pi3p; IGHM; Eif3a; HNRNPU; VP35; PYHIN1
- Q&As
- Reviews
Q&As (7)
Ask a questionMutations in BAZ1B can lead to impaired chromatin remodeling and various diseases.
Dysregulated BAZ1B activity is associated with cancer progression and tumor biology.
Targeting BAZ1B in therapy could help in treating neurodevelopmental disorders and cancers.
BAZ1B is crucial for modifying chromatin structure, thereby regulating gene expression.
BAZ1B plays a role in the DNA damage response, aiding in DNA repair mechanisms.
Its dysfunction is linked to neurodevelopmental disorders through altered gene regulation.
BAZ1B cooperates with other proteins in chromatin remodeling and gene transcription.
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