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BAZ1B

  • Official Full Name

    bromodomain adjacent to zinc finger domain, 1B

  • Overview

    The human WSTF gene is located within the common Williams Syndrome (WS) deletion area at chromosome 7q11.23. Several WSTF gene products have been detected with little difference in length of polypeptides. Functional motifs identified by sequence-homology
  • Synonyms

    BAZ1B; bromodomain adjacent to zinc finger domain, 1B; WBSCR9, WBSCR10; tyrosine-protein kinase BAZ1B; transcription factor WSTF; Williams Beuren syndrome chromosome region 9; Williams Beuren syndrome chromosome region 10; WSTF; hWALp2; williams syndrome;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • GST|His|Strep
  • His
  • His (Fc)
  • Avi
  • His|Flag
  • His|Strep
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BAZ1B-32H Recombinant Human BAZ1B, His&FLAG-tagged E.coli His/Flag
Human BAZ1B-58H Recombinant Human BAZ1B protein, His-tagged E.coli His/Strep 1340-1457
Human BAZ1B-57H Recombinant Human BAZ1B protein, GST-tagged E.coli GST/His/Strep 1340-1457
Human BAZ1B-097H Recombinant Human BAZ1B Protein, GST-tagged Wheat Germ GST
Human BAZ1B-3699H Recombinant Human BAZ1B protein, His-tagged E.coli His 1144-1483 aa
Mouse BAZ1B-2302M Recombinant Mouse BAZ1B Protein Mammalian Cell His
Mouse BAZ1B-971M Recombinant Mouse BAZ1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BAZ1B-971M-B Recombinant Mouse BAZ1B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque BAZ1B-515R Recombinant Rhesus monkey BAZ1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque BAZ1B-343R Recombinant Rhesus Macaque BAZ1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque BAZ1B-343R-B Recombinant Rhesus Macaque BAZ1B Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BAZ1B Related Articles
  • BAZ1B Related Research Area

BAZ1B involved in several pathways and played different roles in them. We selected most pathways BAZ1B participated on our site, such as DNA Double Strand Break Response, DNA Double-Strand Break Repair, DNA Repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with BAZ1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DNA Double Strand Break ResponseUBE2V2;BAZ1B;BRE;CHEK2;FAM175A;KDM4B;EYA3;RAD50;UIMC1
DNA Double-Strand Break RepairBRE;PPP4R2A;THRSP;PPP4R2B;PAXIP1;SMARCA5;CHEK2;PPP4CA;UIMC1
DNA RepairEYA4;UBE2V2;TDP2;CHEK1;DDB1;UIMC1;COPS8;EYA3;FUZ
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaksEYA3;EYA2;KDM4B;KDM4A;EYA4;BAZ1B

BAZ1B has several biochemical functions, for example, ATP binding, chromatin binding, histone kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BAZ1B itself. We selected most functions BAZ1B had, and list some proteins which have the same functions with BAZ1B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPLK4;TTF2;MAPK8B;ACTB;KARS;MAP4K6;PDPK1;ASCC3;UBE2KA
chromatin bindingPHC1;NCOA2;EP300;NEUROD1;NOC3L;MED1;NUPR1;POLE;AIRE
histone kinase activityCCNB1;BAZ1B;CDK1
lysine-acetylated histone bindingATAD2B;PSME4B;BAZ1B;BRD9;MLL1;TAF1;TRIM24;BRD7;BRD2
non-membrane spanning protein tyrosine kinase activityJAK1;PTK2AB;TNK2B;LYN;DYRK1A;TEC;Fert2;YES1;WEE2
protein bindingMST1;SSX5;RPL37A;LRR1;GLS2;Apba1;ICAM4;SPSB3;STAM2
protein tyrosine kinase activityEPHB4A;EPHA4B;PTK7;EPHA7;MAP2K1;CSK;FYNB;BTK;FGFR1A
vitamin D receptor activator activity
zinc ion bindingRNF24;KCMF1;MTF2;NR1D2B;LMO4B;TRAF4;ADAM33;ADAM10;PRKCBP1L

BAZ1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BAZ1B here. Most of them are supplied by our site. Hope this information will be useful for your research of BAZ1B.

SMARCA5; MYH1; NR4A2; Smarca5; BAZ1A; BAZ2A; PHLDA3; pi3p; IGHM; Eif3a; HNRNPU; VP35; PYHIN1

Pfeiffer, MJ; Taher, L; et al. Differences in embryo quality are associated with differences in oocyte composition: A proteomic study in inbred mice. PROTEOMICS 15:675-687(2015).
Hennig, EE; Mikula, M; et al. Comparative kinome analysis to identify putative colon tumor biomarkers. JOURNAL OF MOLECULAR MEDICINE-JMM 90:447-456(2012).
  • Q&As
  • Reviews

Q&As (7)

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How do mutations in the BAZ1B gene affect cellular functions and disease development? 11/15/2021

Mutations in BAZ1B can lead to impaired chromatin remodeling and various diseases.

What are the implications of BAZ1B dysregulation in cancer biology? 03/01/2021

Dysregulated BAZ1B activity is associated with cancer progression and tumor biology.

What potential therapeutic strategies could target BAZ1B in various diseases? 12/22/2019

Targeting BAZ1B in therapy could help in treating neurodevelopmental disorders and cancers.

What is the primary role of BAZ1B in chromatin remodeling and gene regulation? 06/02/2019

BAZ1B is crucial for modifying chromatin structure, thereby regulating gene expression.

What is the function of BAZ1B in DNA damage response and repair? 02/07/2018

BAZ1B plays a role in the DNA damage response, aiding in DNA repair mechanisms.

How does BAZ1B contribute to neurodevelopmental disorders? 01/30/2018

Its dysfunction is linked to neurodevelopmental disorders through altered gene regulation.

How does BAZ1B interact with other chromatin remodelers and transcription factors? 01/05/2018

BAZ1B cooperates with other proteins in chromatin remodeling and gene transcription.

Customer Reviews (3)

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Reviews
08/28/2022

    Efficient and precise, meets research demands.

    08/02/2021

      Critical for our protein research success.

      10/23/2020

        Exceptional service, crucial for our experiments.

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