bche
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  • Official Full Name
  • butyrylcholinesterase
  • Background
  • Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
  • Synonyms
  • BCHE; butyrylcholinesterase; CHE1, cholinesterase 1; cholinesterase; E1; Acylcholine acylhydrolase; Choline esterase II; Pseudocholinesterase; Butyrylcholine esterase; CHE1; CHLE_HUMAN; cholinesterase 1; OTTHUMP00000212636
Cat.#:BCHE-354DTag:His
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog BCHE Protein (1-141 aa), His-tagged
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Cat.#:BCHE-2468HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human BCHE Protein, MYC/DDK-tagged
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Cat.#:BCHE-574HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BCHE Protein, His-tagged
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Cat.#:Bche-575RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Bche Protein, His-tagged
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Cat.#:BCHE-10HTag:His
Source (Host):Trichoplusia ni larval expression systemSpecies:Human
Product nameRecombinant Human BCHE, His-tagged
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Cat.#:BCHE-134HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BCHE Protein, GST-tagged
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Cat.#:BCHE-2533HTag:
Source (Host):CHO-K1Species:Human
Product nameRecombinant Human BCHE
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Cat.#:BCHE-901HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BCHE, His tagged
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Cat.#:Bche-355MTag:His
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Bche, His-tagged
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Cat.#:Bche-910MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Bche, His tagged
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Cat.#:BCHE-6214CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BCHE
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Cat.#:BCHE-26067THTag:
Source (Host):Species:Human
Product nameNative Human BCHE
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Cat.#:BCHE-5291HTag:N/A
Source (Host):Human SerumSpecies:Human
Product nameNative Human Butyrylcholinesterase
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Cat.#:BCHE-8054HTag:N/A
Source (Host):Human SerumSpecies:Human
Product nameNative Human Serum ButyrylcholinEsterase
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Cat.#:BCHE-157HTag:
Source (Host):Horse SerumSpecies:Equine
Product nameNative Horse Serum Butyrylcholinesterase
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Cat.#:BCHE-8ETag:
Source (Host):Species:Equine
Product nameNative Equine Butyrylcholine esterase
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Cat.#:BCHE-2196HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BCHE cell lysate
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Cat.#:BCHE-2286MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BCHE cell lysate
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Cat.#:Kit-0133Tag:
Source (Host):Species:
Product nameButyrylcholinesterase Fluorometric Detection Kit
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Cat.#:Kit-2349Tag:
Source (Host):Species:
Product nameButyrylcholinesterase Activity Kit (Colorimetric)
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Involved Pathway

BCHE involved in several pathways and played different roles in them. We selected most pathways BCHE participated on our site, such as Glycerophospholipid biosynthesis, Irinotecan Pathway, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCHE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycerophospholipid biosynthesis
BCHE; CDIPT; PITPNB; PLBD1; CDS1; PHOSPHO1; STIL; CHKB; PLD4; AWAT1
Irinotecan Pathway
ABCC2; CES1; BCHE; CYP3A5
Metabolism
MED25; CERS4A; PPARGC1B; ACOT12; COX14; NEU4; GLTPA; SACM1LA; SULT1B1; GYG1B
Metabolism of lipids and lipoproteins
FAM213B; ACOT13; Agmo; ACOT12; LMF2; ACOT9.2; CYP27B1; CYP4F11; MED26; LPA
Metabolism of proteins
EEF1A1; MUC21; KCNA6; HYOU1; SERPINA7; EXOSC8; CEACAM21; IGF2B; ST8SIA3; CTSG
Neuronal System
CHRNA1; PPFIA4; KCNH5A; GNGT2B; CACNG2B; PANX1B; KCND3; PPFIA1; ARL6IP5; MYO6
Neurotransmitter Clearance In The Synaptic Cleft
BCHE
Peptide hormone metabolism
GZMH; SLC30A6; RAB27A; MBOAT4; EXOC8; PCSK2; CMA1; SLC38A8; CPE; ACE

Protein Function

BCHE has several biochemical functions, for example, acetylcholinesterase activity, beta-amyloid binding, catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BCHE itself. We selected most functions BCHE had, and list some proteins which have the same functions with BCHE. You can find most of the proteins on our site.
Function
Related Protein
Function acetylcholinesterase activity
Related Protein BCHE; ACHE
Function beta-amyloid binding
Related Protein OLFM1; APOA1; HBA-A2; IDE; APBB2; LDLRAD3; APBB3; NGFR; FBXO2; BCHE
Function catalytic activity
Related Protein HSD17B1; THA1; TIGARB; IMPDH1A; PPM1NB; OLFM4; PBLD1; ALAD; MOXD1L; ALDOAA
Function choline binding
Related Protein BCHE; CRP; CHKA; SLC5A7
Function cholinesterase activity
Related Protein BCHE; CHKA; ACHE; CEL.1; CELL
Function enzyme binding
Related Protein DDX5; PEX7; Txn1; ZNHIT6; UGT1A6; CUTA; UGT1A6B; HDHD2; CAV1; TSPAN14
Function identical protein binding
Related Protein ACTN2; DVL2; SP100; P2RX2; ENTPD2; C1QTNF6; BCAT1; TRIP10; PKD2L1; GYPA

Interacting Protein

BCHE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCHE here. Most of them are supplied by our site. Hope this information will be useful for your research of BCHE.
Sgol2

BCHE Related Articles

Schopfer, LM; Masson, P; et al. Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome. ANALYTICAL BIOCHEMISTRY 461:17-26(2014).
Schneider, JD; Marillonnet, S; et al. Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana. PLANT BIOTECHNOLOGY JOURNAL 12:832-839(2014).