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BDKRB1

  • Official Full Name

    bradykinin receptor B1

  • Overview

    Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Synonyms

    BDKRB1; bradykinin receptor B1; B1R; BKR1; B1BKR; BKB1R; BRADYB1; B1 bradykinin receptor; BK-1 receptor; bradykinin receptor 1; bradykinin B1 receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Chicken
  • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus)
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Macaca mulatta (Rhesus macaque)
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • Sus scrofa (Pig)
  • Tupaia minor (Pigmy tree shrew)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BDKRB1-184H Recombinant Human BDKRB1 Protein, GST-tagged Wheat Germ GST
Human BDKRB1-183H Recombinant Human BDKRB1 Protein, GST-tagged Wheat Germ GST
Human BDKRB1-8471HCL Recombinant Human BDKRB1 293 Cell Lysate HEK293 N/A
Human BDKRB1-1684HF Recombinant Full Length Human BDKRB1 Protein, GST-tagged In Vitro Cell Free System GST 353 amino acids
Human BDKRB1-1563HF Recombinant Full Length Human BDKRB1 Protein, GST-tagged In Vitro Cell Free System GST 353 amino acids
Rat BDKRB1-965R Recombinant Rat BDKRB1 Protein Mammalian Cell His
Rat BDKRB1-623R Recombinant Rat BDKRB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat BDKRB1-623R-B Recombinant Rat BDKRB1 Protein Pre-coupled Magnetic Beads HEK293
Canis lupus familiaris (Dog) (Canis familiaris) RFL34242CF Recombinant Full Length Dog B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-350)
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL9564CF Recombinant Full Length Chlorocebus Aethiops B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-352)
Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus) RFL36031CF Recombinant Full Length Cercopithecus Pygerythrus B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-352)
Homo sapiens (Human) RFL35284HF Recombinant Full Length Human B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-353)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL33721MF Recombinant Full Length Macaca Fascicularis B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-352)
Macaca mulatta (Rhesus macaque) RFL4343MF Recombinant Full Length Macaca Mulatta B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-352)
Mus musculus (Mouse) RFL31546MF Recombinant Full Length Mouse B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-334)
Oryctolagus cuniculus (Rabbit) RFL22366OF Recombinant Full Length Rabbit B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-352)
Rattus norvegicus (Rat) RFL30024RF Recombinant Full Length Rat B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-337)
Sus scrofa (Pig) RFL13011SF Recombinant Full Length Pig B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-353)
Tupaia minor (Pigmy tree shrew) RFL10162TF Recombinant Full Length Tupaia Minor B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system His Full Length (1-352)
Zebrafish BDKRB1-9696Z Recombinant Zebrafish BDKRB1 Mammalian Cell His
Chicken BDKRB1-3615C Recombinant Chicken BDKRB1 Mammalian Cell His
Kit-0989 Intracellular Fluorimetric Hydrogen Peroxide Assay Kit (Green, Optimized for Flow Cytometry) N/A
Kit-1127 BDKRB1 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BDKRB1 Related Research Area

BDKRB1 involved in several pathways and played different roles in them. We selected most pathways BDKRB1 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with BDKRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPLCB2;HTR6;STIM1;GNAQ;CHRM2;ATP2B4;STIM2;ATP2B1A;SLC25A5
Neuroactive ligand-receptor interactionP2RX3A;GABRA2;PRLHR;NR3C1;HTR5AL;TAAR14B;PTGER4C;P2RX8;P2RX4A
Complement and coagulation cascadesCD46;CD59;SERPINA1A;C2;SERPING1;MASP2;C5AR1;C1QC;F3
Inflammatory mediator regulation of TRP channelsIGF1;CAMK2D;HTR2A;PRKACG;CALML3;NGF;TRPA1;SRC;PRKCA
Regulation of actin cytoskeletonARPC5A;EZRB;FGF13B;CHRM5A;ITGB1B.2;CHRM2A;PDGFAB;PFN2L;MYL5
Pathways in cancerFGF20;PIK3R5;IGF1;FGF2;CBLB;PLCB3;GNA12;RALB;CCNE2

BDKRB1 has several biochemical functions, for example, bradykinin receptor activity, peptide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BDKRB1 itself. We selected most functions BDKRB1 had, and list some proteins which have the same functions with BDKRB1. You can find most of the proteins on our site.

Function Related Protein
bradykinin receptor activityBDKRB1;BDKRB2
peptide bindingNUP98;NPFFR1;PPIA;GNRHR;PPIB;LNPEP;GPR22;CSNK1D;CTSL2
protein bindingFANCA;HAND1;ARHGAP24;AGAP2;MTOR;VHLL;MARK3;STAP1;TCTEX1D2

BDKRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BDKRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BDKRB1.

KNG1; KNG1

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