BDKRB1
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Official Full Name
bradykinin receptor B1
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Overview
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] -
Synonyms
BDKRB1; bradykinin receptor B1; B1R; BKR1; B1BKR; BKB1R; BRADYB1; B1 bradykinin receptor; BK-1 receptor; bradykinin receptor 1; bradykinin B1 receptor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Canis lupus familiaris (Dog) (Canis familiaris)
- Chicken
- Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
- Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus)
- Homo sapiens (Human)
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Macaca mulatta (Rhesus macaque)
- Mus musculus (Mouse)
- Oryctolagus cuniculus (Rabbit)
- Rat
- Rattus norvegicus (Rat)
- Sus scrofa (Pig)
- Tupaia minor (Pigmy tree shrew)
- Zebrafish
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | BDKRB1-184H | Recombinant Human BDKRB1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | BDKRB1-183H | Recombinant Human BDKRB1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | BDKRB1-8471HCL | Recombinant Human BDKRB1 293 Cell Lysate | HEK293 | N/A | ||
Human | BDKRB1-1684HF | Recombinant Full Length Human BDKRB1 Protein, GST-tagged | In Vitro Cell Free System | GST | 353 amino acids | |
Human | BDKRB1-1563HF | Recombinant Full Length Human BDKRB1 Protein, GST-tagged | In Vitro Cell Free System | GST | 353 amino acids | |
Rat | BDKRB1-965R | Recombinant Rat BDKRB1 Protein | Mammalian Cell | His | ||
Rat | BDKRB1-623R | Recombinant Rat BDKRB1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | BDKRB1-623R-B | Recombinant Rat BDKRB1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Canis lupus familiaris (Dog) (Canis familiaris) | RFL34242CF | Recombinant Full Length Dog B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-350) | |
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) | RFL9564CF | Recombinant Full Length Chlorocebus Aethiops B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) | |
Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus) | RFL36031CF | Recombinant Full Length Cercopithecus Pygerythrus B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) | |
Homo sapiens (Human) | RFL35284HF | Recombinant Full Length Human B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-353) | |
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) | RFL33721MF | Recombinant Full Length Macaca Fascicularis B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) | |
Macaca mulatta (Rhesus macaque) | RFL4343MF | Recombinant Full Length Macaca Mulatta B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) | |
Mus musculus (Mouse) | RFL31546MF | Recombinant Full Length Mouse B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-334) | |
Oryctolagus cuniculus (Rabbit) | RFL22366OF | Recombinant Full Length Rabbit B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) | |
Rattus norvegicus (Rat) | RFL30024RF | Recombinant Full Length Rat B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-337) | |
Sus scrofa (Pig) | RFL13011SF | Recombinant Full Length Pig B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-353) | |
Tupaia minor (Pigmy tree shrew) | RFL10162TF | Recombinant Full Length Tupaia Minor B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) | |
Zebrafish | BDKRB1-9696Z | Recombinant Zebrafish BDKRB1 | Mammalian Cell | His | ||
Chicken | BDKRB1-3615C | Recombinant Chicken BDKRB1 | Mammalian Cell | His | ||
Kit-0989 | Intracellular Fluorimetric Hydrogen Peroxide Assay Kit (Green, Optimized for Flow Cytometry) | N/A | ||||
Kit-1127 | BDKRB1 CHO-K1 β-Arrestin GPCR Assay Kit | N/A |
- Involved Pathway
- Protein Function
- Interacting Protein
- BDKRB1 Related Research Area
BDKRB1 involved in several pathways and played different roles in them. We selected most pathways BDKRB1 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with BDKRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Calcium signaling pathway | PLCB2;HTR6;STIM1;GNAQ;CHRM2;ATP2B4;STIM2;ATP2B1A;SLC25A5 |
Neuroactive ligand-receptor interaction | P2RX3A;GABRA2;PRLHR;NR3C1;HTR5AL;TAAR14B;PTGER4C;P2RX8;P2RX4A |
Complement and coagulation cascades | CD46;CD59;SERPINA1A;C2;SERPING1;MASP2;C5AR1;C1QC;F3 |
Inflammatory mediator regulation of TRP channels | IGF1;CAMK2D;HTR2A;PRKACG;CALML3;NGF;TRPA1;SRC;PRKCA |
Regulation of actin cytoskeleton | ARPC5A;EZRB;FGF13B;CHRM5A;ITGB1B.2;CHRM2A;PDGFAB;PFN2L;MYL5 |
Pathways in cancer | FGF20;PIK3R5;IGF1;FGF2;CBLB;PLCB3;GNA12;RALB;CCNE2 |
BDKRB1 has several biochemical functions, for example, bradykinin receptor activity, peptide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BDKRB1 itself. We selected most functions BDKRB1 had, and list some proteins which have the same functions with BDKRB1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
bradykinin receptor activity | BDKRB1;BDKRB2 |
peptide binding | NUP98;NPFFR1;PPIA;GNRHR;PPIB;LNPEP;GPR22;CSNK1D;CTSL2 |
protein binding | FANCA;HAND1;ARHGAP24;AGAP2;MTOR;VHLL;MARK3;STAP1;TCTEX1D2 |
BDKRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BDKRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BDKRB1.
KNG1; KNG1
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