BFSP1
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Official Full Name
beaded filament structural protein 1, filensin
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Overview
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
BFSP1; beaded filament structural protein 1, filensin; filensin; CP94; CP115; LIFL H; cytoskeletal protein, 115 KD; lens intermediate filament-like heavy; lens fiber cell beaded-filament structural protein CP 115; LIFL-H;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
BFSP1 involved in several pathways and played different roles in them. We selected most pathways BFSP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BFSP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
BFSP1 has several biochemical functions, for example, protein binding, structural constituent of cytoskeleton, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by BFSP1 itself. We selected most functions BFSP1 had, and list some proteins which have the same functions with BFSP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CNOT6L;CCDC167;C17orf59;BTG3;EIF3J;TTC35;POLL;PPM1F;TEAD4 |
| structural constituent of cytoskeleton | TUBA1A;TUBA1L2;DES;CYLC2;TUBB;TUBB2;SORBS3;EPB42;TUBA8L |
| structural constituent of eye lens | CRYBB1;LIM2.2;LIM2.1;LIM2.5;CRYBB2;CRYGD;LIM2.3;CRYAB;CRYAA |
BFSP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BFSP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BFSP1.
NUP62
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