BCL2L2
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Official Full Name
BCL2-like 2
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Overview
The Bcl-2 family consists of a number of evolutionarily conserved proteins containing Bcl-2 homology domains (BH) that regulate apoptosis through control of mitochondrial membrane permeability and release of cytochrome c (1-3). Four BH domains have been i -
Synonyms
BCL2L2; BCL2-like 2; bcl-2-like protein 2; BCL W; KIAA0271; PPP1R51; protein phosphatase 1; regulatory subunit 51; apoptosis regulator BCL-W; protein phosphatase 1, regulatory subunit 51; BCLW; BCL-W; BCL2-L-2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Dog
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Flag
- GST
- His (Fc)
- Avi
- His|MBP
- SUMO
- Myc
- DDK
- MYC
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- BCL2L2 Related Gene Family
- BCL2L2 Related Research Area
BCL2L2 involved in several pathways and played different roles in them. We selected most pathways BCL2L2 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL2L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MicroRNAs in cancer | SOCS1;TGFB2;MCL1;THBS1;EZR;DNMT3A;TPM1;PDGFRA;CDC25C |
BCL2L2 has several biochemical functions, for example, BH domain binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL2L2 itself. We selected most functions BCL2L2 had, and list some proteins which have the same functions with BCL2L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| BH domain binding | BAK1;BOK;BIK;Bcl2a1b;BCL2A1A;BCL2L2 |
| protein binding | ATP6V1H;LAT2;NFYC;SOX4;GSTM4;CRY2;NCS1;RPL7A;WDR4 |
| protein heterodimerization activity | TLR2;PKNOX1;WHRN;BTBD11;GAD2;TCF3;BDKRB2;SMC3;ENO2 |
| protein homodimerization activity | EPHX2;TERT;HEYL;ACAT1;RENBP;SNRPC;VEGFB;TG;MFF |
BCL2L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL2L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL2L2.
BCL2L11; BIK; BID; TP53BP2; Bmf
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