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BTD

  • Official Full Name

    biotinidase

  • Overview

    Biotinidase functions to recycle biotin in the body by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. Biotinidase has also been shown to have biotinyl-transferase activity. Defects in the biotinidase gene cause multiple carboxylase deficiency.
  • Synonyms

    BTD; biotinidase; EC 3.5.1.12; Biotinase; BTD_HUMAN; OTTHUMP00000160300; OTTHUMP00000209134; OTTHUMP00000209135; OTTHUMP00000209138;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Fc|His
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BTD-8392H Active Recombinant Human BTD, His-tagged CHO His
Human BTD-46H Recombinant Human BTD, His-tagged HEK293 His
Human BTD-355H Recombinant Human BTD, His tagged Human Cell Fc/His
Human BTD-379H Recombinant Human BTD Protein, GST-tagged Wheat Germ GST
Human BTD-8393H Recombinant Human BTD, MYC/DDK-tagged HEK293 Myc/DDK
Human BTD-8395HCL Recombinant Human BTD 293 Cell Lysate HEK293 N/A
Human BTD-1681H Recombinant Human BTD protein, His-tagged E.coli His Ala42~Ala271
Human BTD-8838HFL Recombinant Full Length Human BTD, Flag-tagged Mamanlian cells Flag
Human BTD-0258H Active Recombinant Human BTD protein, His-tagged HEK293 His Met1-Asp543
Human BTD-1666HF Recombinant Full Length Human BTD Protein, GST-tagged In Vitro Cell Free System GST 543 amino acids
Human BTD-0763H Recombinant Human BTD Protein (Ala42-Ala271), His tagged E.coli His Ala42-Ala271
Mouse BTD-2528M Recombinant Mouse BTD Protein Mammalian Cell His
Mouse Btd-1900M Recombinant Mouse Btd Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BTD-1110M Recombinant Mouse BTD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BTD-1110M-B Recombinant Mouse BTD Protein Pre-coupled Magnetic Beads HEK293
Rat BTD-1028R Recombinant Rat BTD Protein Mammalian Cell His
Rat BTD-686R-B Recombinant Rat BTD Protein Pre-coupled Magnetic Beads HEK293
Rat BTD-686R Recombinant Rat BTD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish BTD-4424Z Recombinant Zebrafish BTD Mammalian Cell His
Chicken BTD-4428C Recombinant Chicken BTD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BTD Related Articles

BTD involved in several pathways and played different roles in them. We selected most pathways BTD participated on our site, such as Biotin metabolism, Metabolic pathways, Vitamin digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with BTD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Biotin metabolismOXSM;HLCS;BTD
Metabolic pathwaysPLB1;PTGES2;DAO.1;COX17;CYP4A10;PON2;DPYS;FUT9;CECR1A
Vitamin digestion and absorptionSLC19A3;PNLIP;APOA1;CUBN;SLC46A1;SLC23A1;APOB;MMACHC;LMBRD1

BTD has several biochemical functions, for example, biotinidase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. Some of the functions are cooperated with other proteins, some of the functions could acted by BTD itself. We selected most functions BTD had, and list some proteins which have the same functions with BTD. You can find most of the proteins on our site.

Function Related Protein
biotinidase activitySIRT4;BTD
hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsDPYSL3;BTD;NAAA;DPYSL5;DPYSL5B;CRMP1;DPYSL4;YDJC;DPYSL2B

BTD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BTD here. Most of them are supplied by our site. Hope this information will be useful for your research of BTD.

KIF21B; cona_canen; CCND1; CDCA5; SIKE1

Winkens, T; Pachmann, K; et al. Circulating epithelial cells in patients with thyroid carcinoma Can they be identified in the blood?. NUKLEARMEDIZIN-NUCLEAR MEDICINE 52:7-13(2013).
Kang, UB; Ahn, Y; et al. Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker. BMC CANCER 10:-(2010).
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