cacnb3
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  • Official Full Name
  • calcium channel, voltage-dependent, beta 3 subunit
  • Background
  • This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of;five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also;play a role in the regulation of transcription factors and calcium transport.
  • Synonyms
  • CACNB3; calcium channel, voltage-dependent, beta 3 subunit; voltage-dependent L-type calcium channel subunit beta-3; CAB3; CACB3_HUMAN; CACNLB3; Calcium Channel Voltage Dependent Beta 3 Subunit; Calcium channel voltage-dependent subunit beta 3; Calcium channel subunit beta 3; CACH3B
Cat.#:CACNB3-0273HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CACNB3 Protein, GST-Tagged
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Cat.#:CACNB3-2261HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CACNB3 Protein, MYC/DDK-tagged
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Cat.#:CACNB3-520HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human CACNB3
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Cat.#:CACNB3-1070RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CACNB3 Protein
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Cat.#:CACNB3-602RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CACNB3 Protein, His-tagged
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Cat.#:CACNB3-268HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CACNB3 cell lysate
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Involved Pathway

CACNB3 involved in several pathways and played different roles in them. We selected most pathways CACNB3 participated on our site, such as MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with CACNB3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
STMN1B; PPM1NB; FASLG; RAC2; RAF1A; RASA2; HSP70L; AKT1; MAP3K5; RASA1
Cardiac muscle contraction
CACNA2D1A; COX7B2; COX7B; COX7A1; MYH7; CACNA1D; ATP1B4; UQCRC1; CACNA2D3; TNNI3
Adrenergic signaling in cardiomyocytes
TPM2; RAPGEF4; CACNA2D2; GNAIA; CREB3L2; PPP2CA; CALM2B; CACNA2D1; CAMK2B1; AKT2L
Oxytocin signaling pathway
EEF2K; CACNA2D4; OXTR; NFATC2; PRKAG2; PRKAG1; MAP2K5; ELK1; GNAQ; GNAS
Hypertrophic cardiomyopathy (HCM)
CACNG3; CACNB2; MYL2; ITGA1; CACNA2D3; TGFB2; DMD; MYL3; ITGB6; ITGA9
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ITGAV; CACNB3; JUP; ACTG1; DMD; EMD; ATP2A2; ITGA8; LAMA2; ITGB8
Dilated cardiomyopathy
TNF; TTN; ITGA4; TPM2; CACNB2; TPM1; LMNA; IGF1; TNNI3; SGCB

Protein Function

CACNB3 has several biochemical functions, for example, high voltage-gated calcium channel activity, protein kinase binding, contributes_to voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CACNB3 itself. We selected most functions CACNB3 had, and list some proteins which have the same functions with CACNB3. You can find most of the proteins on our site.
Function
Related Protein
Function high voltage-gated calcium channel activity
Related Protein CACNB1; CACNA1B; CACNB3A; CACNB4A; CACNB2B; CACNA1SB; CACNA1SA; CACNA1C; CACNB3; CACNB4B
Function protein kinase binding
Related Protein CCND2; PTPRR; SPDYA; SLC12A5; CD36; CACNB4; CEP152; NSF; PARN; TRAF4
Function contributes_to voltage-gated calcium channel activity
Related Protein CACNB3; CACNB4; CACNA2D1

Interacting Protein

CACNB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CACNB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CACNB3.
FASLG; SYT1

CACNB3 Related Articles

Murakami, M; Nakagawasai, O; et al. Modified behavioral characteristics following ablation of the voltage-dependent calcium channel beta 3 subunit. BRAIN RESEARCH 1160:102-112(2007).
Endoh, T; et al. Characterization of modulatory effects of postsynaptic metabotropic glutamate receptors on calcium currents in rat nucleus tractus solitarius. BRAIN RESEARCH 1024:212-224(2004).