CADM1A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Zebrafish | CADM1A-6315Z | Recombinant Zebrafish CADM1A | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
CADM1A involved in several pathways and played different roles in them. We selected most pathways CADM1A participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CADM1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Cell adhesion molecules (CAMs) | HLA-G;CDH15;CADM3;HLA-DOA;ICAM2;Siglec1;ITGAV;H2-AA;HLA-DQA2 |
CADM1A has several biochemical functions, for example, cell adhesion molecule binding, protein homodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CADM1A itself. We selected most functions CADM1A had, and list some proteins which have the same functions with CADM1A. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
cell adhesion molecule binding | MSN;NRXN2;PVRL1B;CADM4;PVRL4;NLGN4X;PKP3;CD200;CD1D |
protein homodimerization activity | TFAP2A;MITD1;FBXO4;TYMS;CTBP1;CD247;VPS4B;TRPM8;MYOM3 |
receptor activity | ADIPOR2;LILRB2;NLGN4A;PVRL2L;LILRB3;TLR4;FAS;PAQR5A;ITGB4 |
receptor binding | NRG1;GFRA3;RASA1;ACOX3;TNFSF13B;ADCYAP1;MLYCD;TMED1;IAPP |
CADM1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CADM1A here. Most of them are supplied by our site. Hope this information will be useful for your research of CADM1A.
- Q&As
- Reviews
Q&As (5)
Ask a questionCADM1A is constitutively expressed in both species, primarily in lymphoid tissues and the brain. In European seabass, it is associated with T lymphocytes and increases during the cell-mediated cytotoxic response. In seabream, it is linked to non-specific cytotoxic/natural killer-like cells and correlates with a strong innate cell-mediated cytotoxic response.
When comparing mouse and zebrafish genes, it was noted that intron loss had occurred in both species, resulting in the elongation of certain exons. For instance, zebrafish CAM1A and 1b exons 1 and 2 were found to be identical to mouse CADM1 exon 1. Additionally, mouse CADM4 exons 3 and 4 appeared to have merged into zebrafish exon 3 due to intron loss.
CADM1A transcript levels increased during the innate cell-mediated cytotoxic response but only in seabream HKLs. No such increase was observed in seabass head-kidney leucocytes .
The chromosomal location of the cadm1a gene was determined through radiation hybrid mapping, which placed it on linkage group 21 in zebrafish. This analysis was crucial because it helped confirm whether cadm1a was a duplicate arising from genome duplication and provided evidence of its orthology with related genes.
In European seabass, CADM1A exhibits the highest transcription levels in the liver, brain, thymus, and spleen. In gilthead seabream, CADM1A has the highest expression in the brain, followed by gills, gonad, and thymus.
Customer Reviews (3)
Write a reviewOur research has been elevated thanks to the outstanding quality of this product.
it consistently delivers exceptional results.
We couldn't be happier with the consistently excellent results this protein provides.
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