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CASC4

  • Official Full Name

    cancer susceptibility candidate 4

  • Overview

    The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.
  • Synonyms

    CASC4; cancer susceptibility candidate 4; protein CASC4; DKFZp459F1927; H63; Cancer susceptibility candidate gene 4 protein; CASC4_HUMAN; Gene associated with HER-2/neu overexpression; MGC74708;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Human
  • Mouse
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CASC4-0409H Recombinant Human CASC4 Protein, GST-Tagged Wheat Germ GST
Human CASC4-7843HCL Recombinant Human CASC4 293 Cell Lysate HEK293 N/A
Human CASC4-2904HF Recombinant Full Length Human CASC4 Protein, GST-tagged In Vitro Cell Free System GST 436 amino acids
Mouse CASC4-2742M Recombinant Mouse CASC4 Protein Mammalian Cell His
Mouse CASC4-1235M Recombinant Mouse CASC4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CASC4-1235M-B Recombinant Mouse CASC4 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL12938BF Recombinant Full Length Bovine Protein Casc4(Casc4) Protein, His-Tagged E.coli expression system His Full Length (1-380)
Chicken CASC4-2270C Recombinant Chicken CASC4 Mammalian Cell His
  • CASC4 Related Articles

CASC4 involved in several pathways and played different roles in them. We selected most pathways CASC4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CASC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CASC4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CASC4 itself. We selected most functions CASC4 had, and list some proteins which have the same functions with CASC4. You can find most of the proteins on our site.

Function Related Protein

CASC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CASC4.

Chiang, HC; Wang, CK; et al. Differential Distribution of CYP2A6 and CYP2A13 in the Human Respiratory Tract. RESPIRATION 84:319-326(2012).
Melchor, L; Saucedo-Cuevas, LP; et al. Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes. BREAST CANCER RESEARCH 11:-(2009).
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