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CATSPER2

  • Official Full Name

    cation channel, sperm associated 2

  • Overview

    Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene. Additional splice variants have been described but their full-length nature has not been determined.
  • Synonyms

    CATSPER2; cation channel, sperm associated 2; cation channel sperm-associated protein 2; Cation channel sperm associated 2; Cation channel sperm associated protein 2; Catsper 2; MGC33346; Putative ion channel protein CATSPER2 variant 1; Putative ion channel protein CATSPER2 variant 2; Putative ion channel protein CATSPER2 variant 3; Sperm associated cation channel 2; Sperm ion channel;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CATSPER2-2733H Recombinant Human CATSPER2 protein, His-tagged E.coli His 1 - 110 aa
Mouse CATSPER2-2767M Recombinant Mouse CATSPER2 Protein Mammalian Cell His
Mouse CATSPER2-1254M-B Recombinant Mouse CATSPER2 Protein Pre-coupled Magnetic Beads HEK293
Mouse CATSPER2-1254M Recombinant Mouse CATSPER2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CATSPER2-1151R Recombinant Rat CATSPER2 Protein Mammalian Cell His
Rat CATSPER2-809R-B Recombinant Rat CATSPER2 Protein Pre-coupled Magnetic Beads HEK293
Rat CATSPER2-809R Recombinant Rat CATSPER2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL18623HF Recombinant Full Length Human Cation Channel Sperm-Associated Protein 2(Catsper2) Protein, His-Tagged E.coli expression system His Full Length (1-530)
Mus musculus (Mouse) RFL34640MF Recombinant Full Length Mouse Cation Channel Sperm-Associated Protein 2(Catsper2) Protein, His-Tagged E.coli expression system His Full Length (1-588)
Rattus norvegicus (Rat) RFL35112RF Recombinant Full Length Rat Cation Channel Sperm-Associated Protein 2(Catsper2) Protein, His-Tagged E.coli expression system His Full Length (1-584)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CATSPER2 involved in several pathways and played different roles in them. We selected most pathways CATSPER2 participated on our site, such as Fertilization, Reproduction, Sperm Motility And Taxes, which may be useful for your reference. Also, other proteins which involved in the same pathway with CATSPER2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FertilizationZP3;CATSPER3;HVCN1;CATSPERB;IZUMO1;ADAM20;Acr;ADAM2;ADAM21
ReproductionIZUMO4;ZP2;OVGP1;CATSPERB;ADAM21;CATSPERG2;CATSPER1;CATSPER2;IZUMO1
Sperm Motility And TaxesCATSPERG2;CATSPER1;CATSPER3;CATSPERB;CATSPERG1;HVCN1;CATSPER2;TMEM146

CATSPER2 has several biochemical functions, for example, calcium activated cation channel activity, calcium channel activity, ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CATSPER2 itself. We selected most functions CATSPER2 had, and list some proteins which have the same functions with CATSPER2. You can find most of the proteins on our site.

Function Related Protein
calcium activated cation channel activityTRPM5;TRPM4;ANO10;ANO6;CATSPER1;TMEM63C;PKD2L1;CALHM1;TRPM4C
calcium channel activitySLC24A2;TRPC7B;PDE2A;AKR1C1;ORAI1B;CACNA1SA;PKD1;TRPC4B;RYR1B
ion channel activityP2RX4B;CHRNB1L;FXYD6L;KCNC1A;CLCN3;SCN8AB;FXYD7;SCN1LAB;P2RX3B
voltage-gated ion channel activityCLCN3;CLIC1;KCNH5;CATSPER2;TMEM37;CLIC5B;CYBB;SCN8AA;SCN12AA

CATSPER2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CATSPER2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CATSPER2.

Ywhae

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