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PROCR

  • Official Full Name

    protein C receptor, endothelial

  • Overview

    The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
  • Synonyms

    PROCR; protein C receptor, endothelial; CCCA; EPCR; CCD41; endothelial protein C receptor; APC receptor; centrocyclin; CD201 antigen; activated protein C receptor; cell cycle, centrosome-associated protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • hFc
  • His
  • Fc
  • Fc|His
  • GST|His
  • His (Fc)
  • Avi
  • human|IgG1|Fc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PROCR-589H Recombinant Human PROCR protein, His-tagged E.coli His Thr63~Ser205 (Accession # Q9UNN8)
Human PROCR-8575H Recombinant Human PROCR protein, Fc-tagged HEK293 human/IgG1/Fc Ser18-Thr209
Human PROCR-568H Recombinant Human PROCR Protein, GST-His-tagged E.coli GST/His
Human PROCR-145H Recombinant Human PROCR, His-tagged E.coli His 18-210aa
Human PROCR-529H Recombinant Human PROCR protein, His-tagged HEK293 His Ser18-Thr209
Human PROCR-1272HCL Recombinant Human PROCR cell lysate Human Cell N/A
Human PROCR-3909H Recombinant Human PROCR Protein (Met1-Thr209), C-His tagged Mammalian cells C-His Met1-Thr209
Human PROCR-010H Recombinant Human PROCR Protein, His-tagged E.coli His
Human PROCR-419H Recombinant Human PROCR Protein, Fc-tagged HEK293 Fc 238
Human PROCR-418H Recombinant Human PROCR Protein, His-tagged HEK293 His 238
Human PROCR-0233H Recombinant Human PROCR protein, Fc-tagged HEK293 Fc Met1-Thr209
Human PROCR-1113H Recombinant Human PROCR Protein (Ser18-Ser210), N-His tagged E.coli N-His Ser18-Ser210
Human PROCR-3433H Recombinant Human PROCR Protein (Ser18-Ser210), C-His tagged Mammalian cells C-His Ser18-Ser210
Human PROCR-0627H Recombinant Human PROCR protein, Fc-tagged HEK293 Fc Ser18-Thr209
Mouse Procr-7004M Recombinant Mouse Procr protein(Met1-Ser214), hFc-tagged HEK293 C-hFc Met1-Ser214
Mouse Procr-590M Recombinant Mouse Procr protein, His-tagged E.coli His Ile32~Phe167 (Accession # Q64695)
Mouse Procr-7005M Recombinant Mouse Procr, His tagged Human Cell His
Mouse PROCR-1717MCL Recombinant Mouse PROCR cell lysate Human Cell N/A
Rat PROCR-4711R Recombinant Rat PROCR Protein Mammalian Cell His
Rat Procr-591R Recombinant Rat Procr protein, His-tagged E.coli His Glu59~Gly217 (Accession # Q4V8I1)
Rat Procr-8791R Recombinant Rat Procr, His tagged Human Cell His
Rat PROCR-1174RCL Recombinant Rat PROCR cell lysate Human Cell N/A
Rat PROCR-4370R Recombinant Rat PROCR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PROCR-4370R-B Recombinant Rat PROCR Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus PROCR-126C Recombinant Cynomolgus PROCR protein, hFc-tagged HEK293 hFc Met1-Thr209
Cynomolgus Monkey PROCR-121C Recombinant Cynomolgus PROCR, Fc tagged Human Cell Fc/His
Cynomolgus Monkey PROCR-122C Recombinant Cynomolgus PROCR, His tagged Human Cell His
Cynomolgus Monkey PROCR-885CCL Recombinant Cynomolgus PROCR cell lysate Human Cell N/A
Chicken PROCR-3278C Recombinant Chicken PROCR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PROCR Related Articles
  • PROCR Related Research Area

PROCR involved in several pathways and played different roles in them. We selected most pathways PROCR participated on our site, such as Cell surface interactions at the vascular wall, Common Pathway of Fibrin Clot Formation, Formation of Fibrin Clot (Clotting Cascade), which may be useful for your reference. Also, other proteins which involved in the same pathway with PROCR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell surface interactions at the vascular wallSLC3A2B;AMICA1;CXADR;DOK2;ANGPT2A;PPIA;SLC16A8;CD177;SLC16A1
Common Pathway of Fibrin Clot FormationSERPINE2;CFHL1;PROCR;CD177;CFHL2;F13A1A.1;SERPINA1L;LOC100514666;PROCA
Formation of Fibrin Clot (Clotting Cascade)SERPINA1L;PRTN3;F9B;F3A;CFHL1;CD177;F13A1B;LOC100514666;PROCA
HemostasisDGKQ;KIF2B;NFE2;MAFGA;KIF22;IGF2B;GATA2;ZFPM2A;KIF4

PROCR has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PROCR itself. We selected most functions PROCR had, and list some proteins which have the same functions with PROCR. You can find most of the proteins on our site.

Function Related Protein
protein bindingAPOBEC3G;SLC9A3R1;MEP1A;SRPX2;MAP4;SH3BP1;ADAM9;KCNA2;RAB11FIP2
receptor activityMED17;IGSF1;RNF139;CD46;GRIA2B;VPREB1;CADM1A;KIR2DL1;KLRB1F

PROCR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PROCR here. Most of them are supplied by our site. Hope this information will be useful for your research of PROCR.

F2R; ganglioside_gm1; DMTN; CAV1

Esser, N; Paquot, N; et al. Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease. EXPERT OPINION ON INVESTIGATIONAL DRUGS 24:283-307(2015).
Sharaf, H; Matou-Nasri, S; et al. Advanced glycation endproducts increase proliferation, migration and invasion of the breast cancer cell line MDA-MB-231. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:429-441(2015).
  • Q&As
  • Reviews

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Customer Reviews (3)

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Reviews
10/02/2021

    I am deeply impressed by the performance and quality of this protein reagent.

    09/16/2017

      The performance of the protein reagent has consistently been stable, and I have complete trust in it.

      07/31/2017

        The consistently stable and reliable performance of this protein reagent renders it overwhelmingly indispensable.

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