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CCNF

  • Official Full Name

    cyclin F

  • Overview

    This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
  • Synonyms

    CCNF; cyclin F; cyclin-F; FBX1; FBXO1; F box only protein 1; G2 mitotic specific cyclin F; OTTHUMP00000159081; F-box only protein 1; G2/mitotic-specific cyclin-F;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCNF-0668H Recombinant Human CCNF Protein, GST-Tagged Wheat Germ GST
Human CCNF-7708HCL Recombinant Human CCNF 293 Cell Lysate HEK293 N/A
Human CCNF-2973HF Recombinant Full Length Human CCNF Protein, GST-tagged In Vitro Cell Free System GST 786 amino acids
Mouse CCNF-2994M Recombinant Mouse CCNF Protein Mammalian Cell His
Mouse CCNF-1407M Recombinant Mouse CCNF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CCNF-1407M-B Recombinant Mouse CCNF Protein Pre-coupled Magnetic Beads HEK293
Rat CCNF-1223R Recombinant Rat CCNF Protein Mammalian Cell His
Rat CCNF-881R Recombinant Rat CCNF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CCNF-881R-B Recombinant Rat CCNF Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CCNF-700R Recombinant Rhesus monkey CCNF Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCNF-528R Recombinant Rhesus Macaque CCNF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CCNF-528R-B Recombinant Rhesus Macaque CCNF Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CCNF-11781Z Recombinant Zebrafish CCNF Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CCNF Related Articles

CCNF involved in several pathways and played different roles in them. We selected most pathways CCNF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CCNF has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNF itself. We selected most functions CCNF had, and list some proteins which have the same functions with CCNF. You can find most of the proteins on our site.

Function Related Protein
protein bindingKCNS2;EIF4A2;ADAM12;NEBL;PTPN23;RIN1;PYROXD1;NCF2;ZNHIT6

CCNF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNF here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNF.

CCP110; RRM2; SKP1

Wu, BB; Yuan, TY; et al. Construction, Expression and Characterization of a Single Chain Variable Fragment Antibody Against Human Myostatin. PROTEIN AND PEPTIDE LETTERS 21:45-51(2014).
Yu, XM; Wang, L; et al. Wnt5a inhibits hypoxia-induced pulmonary arterial smooth muscle cell proliferation by downregulation of beta-catenin. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 304:L103-L111(2013).
  • Q&As
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