Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

Cdk5rap1

Official Full Name

CDK5RAP1 CDK5 regulatory subunit associated protein 1 [ Homo sapiens ]
Overview

This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis.
Synonyms

2310066P17Rik; C20orf34; C42; CDK5 activator binding protein C42; CDK5 activator binding protein C42 like; CDK5 regulatory subunit associated protein 1; CDK5RAP1.3; CDK5RAP1.4; CGI 05; HSPC167; OTTMUSP00000016976; RP23-154J12.6; RP5-1187J4.1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDK5RAP1-1025H	Recombinant Human CDK5RAP1 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CDK5RAP1-11052H	Recombinant Human CDK5RAP1, GST-tagged	E.coli	GST	239-587a.a.	$319 / 25ug
Human	CDK5RAP1-7624HCL	Recombinant Human CDK5RAP1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CDK5RAP1-3138H	Recombinant Human CDK5RAP1 Protein, His-tagged	E.coli	His		Inquiry
Human	CDK5RAP1-3127HF	Recombinant Full Length Human CDK5RAP1 Protein, GST-tagged	In Vitro Cell Free System	GST	587 amino acids	Inquiry
Rat	CDK5RAP1-1307R	Recombinant Rat CDK5RAP1 Protein	Mammalian Cell	His		Inquiry
Rat	CDK5RAP1-965R	Recombinant Rat CDK5RAP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	CDK5RAP1-965R-B	Recombinant Rat CDK5RAP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Cdk5rap1 Related Articles

Cdk5rap1 involved in several pathways and played different roles in them. We selected most pathways Cdk5rap1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Cdk5rap1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

Cdk5rap1 has several biochemical functions, for example, NOT 4 iron, 4 sulfur cluster binding, metal ion binding, NOT methylthiotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cdk5rap1 itself. We selected most functions Cdk5rap1 had, and list some proteins which have the same functions with Cdk5rap1. You can find most of the proteins on our site.

Function	Related Protein
NOT 4 iron, 4 sulfur cluster binding
metal ion binding	ZNF511;PDE6B;ZNF804A;PRDM1;RNF180;ZC3H3;ZNF79;SCRT1A;EGR3
NOT methylthiotransferase activity
protein complex binding	NDUFA9;C8B;HADHA;PPP4C;ATP6V0D1;TAB1;LCA5;SKIL;FBLN1
protein kinase binding	STAP1;PTEN;CDC25C;CD24;FAM83A;SOCS1;FBXW5;ACSL3;PLK1
protein kinase regulator activity	FAF1;CDK5RAP1;KIDINS220B;ANKRD54;CSNK2B;RAC2;APC;KIDINS220;CDC37

Cdk5rap1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cdk5rap1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cdk5rap1.

EXOSC5; EXOSC3

Xie, P; Wei, FY; et al. Quantitative PCR Measurement of tRNA 2-Methylthio Modification for Assessing Type 2 Diabetes Risk. CLINICAL CHEMISTRY 59:1604-1612(2013).

Brambillasca, S; Altkrueger, A; et al. CDK5 Regulatory Subunit-associated Protein 1-Like 1 (CDKAL1) Is a Tail-anchored Protein in the Endoplasmic Reticulum (ER) of Insulinoma Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 287:41808-41819(2012).