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CELF2

  • Official Full Name

    CUGBP, Elav-like family member 2

  • Overview

    Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms

    CELF2; CUGBP, Elav-like family member 2; CUG triplet repeat, RNA binding protein 2 , CUG triplet repeat, RNA binding protein 2 , CUGBP2; CUGBP Elav-like family member 2; BRUNOL3; Etr 3; NAPOR 2; Bruno-like protein 3; Cardiac elav type RNA binding protein; CELF-2; CELF2_HUMAN; CUG BP2; CUG triplet repeat RNA-binding protein 2; CUG-BP- and ETR-3-like factor 2; CUG-BP2; dJ323N1.1; elav type RNA binding protein; ELAV-type RNA-binding protein 3; ETR-3; HGNC:2550; hNAPOR; NAPOR; Neuroblastoma apoptosis-related RNA-binding protein; Neuroplastoma apoptosis related RNA binding protein 3; RNA binding protein BRUNOL3; RNA-binding protein BRUNOL-3; OTTHUMP00000019076; OTTHUMP00000019077; OTTHUMP00000019078; CUG triplet repeat, RNA binding protein 2; ETR3; CUGBP2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CELF2-2128H Recombinant Human CELF2 Protein, GST-tagged Wheat Germ GST
Human CELF2-422HCL Recombinant Human CELF2 cell lysate N/A
Human CELF2-2392HF Recombinant Full Length Human CELF2 Protein, GST-tagged In Vitro Cell Free System GST 521 amino acids
Human CELF2-1404H Recombinant Human CELF2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CELF2-3186H Recombinant Human CELF2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CELF2-2423H Recombinant Human CELF2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse CELF2-3273M Recombinant Mouse CELF2 Protein Mammalian Cell His
Mouse CELF2-1568M-B Recombinant Mouse CELF2 Protein Pre-coupled Magnetic Beads HEK293
Mouse CELF2-1568M Recombinant Mouse CELF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Celf2-979M Recombinant Mouse Celf2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CELF2-1331R Recombinant Rat CELF2 Protein Mammalian Cell His
Rat CELF2-989R-B Recombinant Rat CELF2 Protein Pre-coupled Magnetic Beads HEK293
Rat CELF2-989R Recombinant Rat CELF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CELF2-9751Z Recombinant Zebrafish CELF2 Mammalian Cell His
Chicken CELF2-5833C Recombinant Chicken CELF2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CELF2 involved in several pathways and played different roles in them. We selected most pathways CELF2 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CELF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA processingPTBP1;PTBP2;CLK1;ZFP622;SUGP1;EIF4E3;PRMT2;SF3A1;RAVER1

CELF2 has several biochemical functions, for example, RNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CELF2 itself. We selected most functions CELF2 had, and list some proteins which have the same functions with CELF2. You can find most of the proteins on our site.

Function Related Protein
RNA bindingEIF1AXA;JMJD6;KHDRBS1;RNMT;DPPA5;RPS4Y1;PTBP1B;SMN1;RNASET2
nucleotide bindingVMHC;DQX1;SLTM;PTK2AA;ABCC8;UBE2IB;CSNK1DB;RAD51L3;RIPK4
poly(A) RNA bindingPARP1;COX4I2;NOVA1;HSPB1;KIF1C;UTP18;APOBEC3B;SBDS;HIST1H4F

CELF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CELF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CELF2.

GRB2; PCBP1; ribF; ssrna_cg; PTBP3; FN1

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