cenpc1
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  • Official Full Name
  • centromere protein C 1
  • Background
  • Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.
  • Synonyms
  • CENPC1; centromere protein C 1; CENP C; CENPC; hcp 4; MIF2; Centromere autoantigen C1; ICEN7; CENP-C 1; OTTHUMP00000218847; centromere autoantigen C; interphase centromere complex protein 7; hcp-4; CENP-C
Cat.#:CENPC1-11094HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPC1, GST-tagged
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Cat.#:CENPC1-3283MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CENPC1 Protein
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Cat.#:CENPC1-7585HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CENPC1 293 Cell Lysate
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Involved Pathway

CENPC1 involved in several pathways and played different roles in them. We selected most pathways CENPC1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPC1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
DYNC1H1; RBBP4; MAD2L1; CDKN1B; SGOL2; LIN54; RAD9A; SETB; OFD1; CKAP5
Cell Cycle, Mitotic
NDC80; APITD1; PHF8; DULLARD; CENPN; CCP110; ITGB3BP; NIPBL; SKA2; PDS5A
Chromosome Maintenance
RBBP7; CENPI; CENPN; MIS18A; PANE1; CENPC1; APITD1; RUVBL2; CENPQ; CENPO
Deposition of new CENPA-containing nucleosomes at the centromere
NPM1; ITGB3BP; MIS18A; RBBP4; CENPO; CENPA; SMARCA5; APITD1; CENPK; CENPP
M Phase
NDEL1A; ARPP19B; CENPH; SKA2; CENPK; CDCA5; APITD1; CTDNEP1; NEK9; GORASP2
Mitotic Anaphase
CENPN; DSN1; CENPL; ERCC6L; AHCTF1; INCENP; ZWINT; CENPI; WAPAL; PANE1
Mitotic Metaphase and Anaphase
ERCC6L; SGOL1; WAPAL; CENPK; NSL1; DSN1; SKA2; PMF1; SGOL2; LEMD3
Mitotic Prometaphase
SPC25; MLF1IP; ZWILCH; CENPP; CCDC99; SMC2; NUF2; NSL1; NCAPD2; CENPI

Protein Function

CENPC1 has several biochemical functions, for example, DNA binding, centromeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPC1 itself. We selected most functions CENPC1 had, and list some proteins which have the same functions with CENPC1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein HOXC9A; DHX9; ARID4A; KLF7; RORCA; ZNF829; ING2; DMBX1A; MEIOB; TRIM33
Function centromeric DNA binding
Related Protein KIF2C; MSH2; ZW10; CENPC1; CENPB; MLH3; MSH3

Interacting Protein

CENPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPC1.
MIS12; DAXX; ZWINT; TCEB1; MAPK14; q9wmx2-pro_0000037551; NUP153; JAK3; CENPQ; Kif2c; CENPO; Cenph; RAD21; SGOL1; POGZ; AURKB