cenpk
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  • Official Full Name
  • centromere protein K
  • Background
  • CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM;117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006;(PubMed 16622420)).
  • Synonyms
  • CENPK; centromere protein K; CENP K; FKSG14; SOLT; protein AF-5alpha; leucine zipper protein FKSG14; SoxLZ/Sox6-binding protein Solt; interphase centromere complex protein 37; P33; CENP-K; AF5alpha
Cat.#:CENPK-1120HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CENPK Protein, GST-Tagged
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Cat.#:CENPK-3288MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CENPK Protein
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Cat.#:CENPK-3455CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CENPK
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Cat.#:CENPK-8186ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CENPK
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Cat.#:CENPK-7582HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CENPK 293 Cell Lysate
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Involved Pathway

CENPK involved in several pathways and played different roles in them. We selected most pathways CENPK participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPK were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
CHEK1; SMC1AL; CDKN2A; NEK6; NCAPG; NUP35; YWHAQB; POT1A; DPF1; RAD21
Cell Cycle, Mitotic
TMPO; NDEL1B; PANE1; CENPA; ERCC6L; SKA1; NIPBLA; CDK11B; VRK2; CENPN
Chromosome Maintenance
TERF2; CENPW; ACD; POT1; CENPI; OIP5; TERF2IP; CENPL; DNA2; CENPK
Deposition of new CENPA-containing nucleosomes at the centromere
CENPA; HJURP; CENPC1; RBBP4; CENPW; CENPN; SMARCA5; MLF1IP; CENPH; OIP5
M Phase
SKA1; VRK1; B9D2; CDCA5; NCAPG; NUDC; SETB; CENPK; TMEM188; PMF1
Mitotic Anaphase
LEMD3; CDCA5; CENPI; PDS5A; CENPC1; PMF1; RCC2; CENPE; NDEL1; DSN1
Mitotic Metaphase and Anaphase
CDCA5; CENPN; INCENP; CCDC99; PMF1; LEMD3; NDEL1; SPC24; DSN1; SKA2
Mitotic Prometaphase
NCAPG; NDEL1A; CENPH; CENPO; NUF2; NDEL1B; NSL1; SMC2; SMC4; CCDC99

Protein Function

CENPK has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPK itself. We selected most functions CENPK had, and list some proteins which have the same functions with CENPK. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein MRPL23; DDR2; NGF; BLOC1S1; TTYH2; AREG; FHL3; ARID1A; SHOC2; THRAP3

Interacting Protein

CENPK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPK here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPK.
q86v28_human; MRFAP1L1; CENPH; HSPB1; KDM5C; ITGB3BP; CENPU; CENPQ; Cenpi; CENPO; Cenph