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CENPL

  • Official Full Name

    centromere protein L

  • Overview

    CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006)
  • Synonyms

    CENP-L; C1orf155; dJ383J4.3; RP3-383J4.1; centromere protein L;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CENPL-11098H Recombinant Human CENPL, His-tagged E.coli His 1-364a.a.
Human CENPL-1122H Recombinant Human CENPL Protein, GST-Tagged Wheat Germ GST
Human CENPL-7581HCL Recombinant Human CENPL 293 Cell Lysate HEK293 N/A
Human CENPL-3769H Recombinant Human CENPL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CENPL-3142HF Recombinant Full Length Human CENPL Protein, GST-tagged In Vitro Cell Free System GST 390 amino acids
Mouse Cenpl-2105M Recombinant Mouse Cenpl Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat CENPL-1334R Recombinant Rat CENPL Protein Mammalian Cell His
Rat CENPL-992R-B Recombinant Rat CENPL Protein Pre-coupled Magnetic Beads HEK293
Rat CENPL-992R Recombinant Rat CENPL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CENPL-812R Recombinant Rhesus monkey CENPL Protein, His-tagged Mammalian Cell His
Rhesus Macaque CENPL-638R Recombinant Rhesus Macaque CENPL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CENPL-638R-B Recombinant Rhesus Macaque CENPL Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CENPL-1165Z Recombinant Zebrafish CENPL Mammalian Cell His
Chicken CENPL-1706C Recombinant Chicken CENPL Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CENPL Related Articles

CENPL involved in several pathways and played different roles in them. We selected most pathways CENPL participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleYWHAQA;SMC1B;MAPRE1;OIP5;TERF1;FAM175A;CUL1;AURKB;TFDP1A
Cell Cycle, MitoticE2F2;DNA2;DBF4;ENSAB;TUBB4B;VRK2;OFD1;PDS5A;PIANP
Chromosome MaintenanceCENPI;RBBP7;POT1;RUVBL2;CENPL;HJURP;RBBP4;CENPH;MLF1IP
Deposition of new CENPA-containing nucleosomes at the centromereCENPI;APITD1;MIS18A;CENPP;HJURP;MLF1IP;SMARCA5;RBBP7;CENPW
M PhaseCENPN;VRK1;NDC80;VRK2;NCAPG2;ERCC6L;NIPBL;LEMD3;MLF1IP
Mitotic AnaphaseCENPC1;AHCTF1;TMPO;B9D2;ZWINT;CENPO;CLIP1;ANKLE2;PDS5A
Mitotic Metaphase and AnaphaseZWILCH;NUDC;CDCA8;NUF2;CENPK;CENPN;KNTC1;CENPL;INCENP
Mitotic PrometaphaseSPDL1;PANE1;CENPN;PDS5A;CLIP1;NCAPH;AHCTF1;PMF1;SGOL1

CENPL has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPL itself. We selected most functions CENPL had, and list some proteins which have the same functions with CENPL. You can find most of the proteins on our site.

Function Related Protein
protein bindingDCP1A;RAB39A;GRHL2;USP13;KIT;LGALS14;SLC3A2;KIAA0368;SOCS7

CENPL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPL here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPL.

FAM9B; JMJD6; Cenph

Dunemann, F; Schrader, O; et al. Characterization of Centromeric Histone H3 (CENH3) Variants in Cultivated and Wild Carrots (Daucus sp.). PLOS ONE 9:-(2014).
Saito, A; Muro, Y; et al. Low prevalence of autoantibodies to CENP-H, -I, -K, -L, -M, -N, -T and -U in a Japanese cohort of anti-centromere positive samples. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 35:57-63(2013).
  • Q&As
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