cenpo
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  • Official Full Name
  • centromere protein O
  • Background
  • This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • Synonyms
  • CENPO; centromere protein O; CENP-O; MCM21R; ICEN-36; centromeric protein O; interphase centromere complex protein 36;
Cat.#:CENPO-1123HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CENPO Protein, GST-Tagged
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Cat.#:CENPO-3183HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPO Protein, GST/His-tagged
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Cat.#:CENPO-11101HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPO, GST-tagged
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Cat.#:CENPO-2773CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CENPO
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Cat.#:CENPO-6038ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CENPO
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Cat.#:CENPO-7578HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CENPO 293 Cell Lysate
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Involved Pathway

CENPO involved in several pathways and played different roles in them. We selected most pathways CENPO participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
SMC1AL; TBC1D8; CENPC1; TTK; CHEK1; ANAPC11; HAUS2; DPF1; TUBB4A; CEP78
Cell Cycle, Mitotic
CENPI; TMEM188; CDKN2D; B9D2; SGOL1; CEP290; NCAPH; NUPL2; TUBGCP3; OFD1
Chromosome Maintenance
ITGB3BP; SMARCA5; CENPQ; MLF1IP; TERF2IP; CENPP; RBBP7; HJURP; CENPC1; ACD
Deposition of new CENPA-containing nucleosomes at the centromere
CENPN; HJURP; CENPP; NPM1; OIP5; PANE1; MIS18BP1; CENPA; CENPI; RBBP7
M Phase
SPC25; VRK2; CDCA8; PMF1; SMC4; ERCC6L; KIF18A; ENSAA; KIF2B; MIS12
Mitotic Anaphase
MIS12; PANE1; CENPO; WAPAL; CENPC1; CENPE; CDCA5; INCENP; SPC24; ZWILCH
Mitotic Metaphase and Anaphase
WAPAL; NUDC; ITGB3BP; CENPL; MIS12; RANGAP1B; NDEL1A; SPC24; CENPQ; CENPE
Mitotic Prometaphase
ZWINT; SMC2; CENPO; NDEL1; CENPN; NCAPG; CDCA8; CENPK; ZW10; B9D2

Protein Function

CENPO has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPO itself. We selected most functions CENPO had, and list some proteins which have the same functions with CENPO. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein TUBGCP3; TNFSF12; ATF3; PSMB10; RHOG; CSRP2; LRRC75A-AS1; GAGE1; MTMR6; SNAPC5

Interacting Protein

CENPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPO here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPO.
CEP170P1; CENPP; NECAB2; FOS; RNF40; STRA13; PABPN1; PLXNB1; SEC22B