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CENPT

  • Official Full Name

    centromere protein T

  • Overview

    The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which;the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the;presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an;additional factor required for centromere assembly (Foltz et al., 2006 (PubMed 16622419)).
  • Synonyms

    CENPT; centromere protein T; C16orf56, chromosome 16 open reading frame 56; CENP T; FLJ13111; C16orf56; CENP-T; CENPT_HUMAN; Chromosome 16 open reading frame 56; ICEN22; Interphase centromere complex protein 22;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CENPT-1127H Recombinant Human CENPT Protein, GST-Tagged Wheat Germ GST
Human CENPT-7575HCL Recombinant Human CENPT 293 Cell Lysate HEK293 N/A
Human CENPT-3146HF Recombinant Full Length Human CENPT Protein, GST-tagged In Vitro Cell Free System GST 299 amino acids
Human CENPT-5871H Recombinant Human CENPT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse CENPT-3295M Recombinant Mouse CENPT Protein Mammalian Cell His
Mouse CENPT-1584M-B Recombinant Mouse CENPT Protein Pre-coupled Magnetic Beads HEK293
Mouse Cenpt-2109M Recombinant Mouse Cenpt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CENPT-1584M Recombinant Mouse CENPT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CENPT-1337R Recombinant Rat CENPT Protein Mammalian Cell His
Rat CENPT-995R-B Recombinant Rat CENPT Protein Pre-coupled Magnetic Beads HEK293
Rat CENPT-995R Recombinant Rat CENPT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CENPT-400C Recombinant Cynomolgus CENPT Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CENPT-148C-B Recombinant Cynomolgus Monkey CENPT Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CENPT-148C Recombinant Cynomolgus Monkey CENPT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CENPT-4705C Recombinant Chicken CENPT Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CENPT Related Articles

CENPT involved in several pathways and played different roles in them. We selected most pathways CENPT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CENPT has several biochemical functions, for example, endonuclease activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPT itself. We selected most functions CENPT had, and list some proteins which have the same functions with CENPT. You can find most of the proteins on our site.

Function Related Protein
endonuclease activityFEN1;PPP1R8;ENDOG;ANG4;RNASE7;EAR5;EAR1;RNASEL4;NTHL1
metal ion bindingNUDT15;ZNF23;PRKCQ;TNNI1;ZNF182;ZFP488;ADNP2;GEN1;PRDM8B
protein bindingCCR1;ANXA1;LILRB2;CXCL2;CD177;MALL;CMTM2A;NEUROD1;GRHL2

CENPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPT here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPT.

CENPW; APITD1; TCEA2; SNCB; DHX29; PPCDC; ITGB3BP; CENPU; CENPQ; CENPO; Cenph

Song, G; Hu, CJ; et al. New Centromere Autoantigens Identified in Systemic Sclerosis Using Centromere Protein Microarrays. JOURNAL OF RHEUMATOLOGY 40:461-468(2013).
Saito, A; Muro, Y; et al. Low prevalence of autoantibodies to CENP-H, -I, -K, -L, -M, -N, -T and -U in a Japanese cohort of anti-centromere positive samples. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 35:57-63(2013).
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