The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined.
CEP350; centrosomal protein 350kDa; centrosome-associated protein 350; CAP350; centrosome associated protein 350; KIAA0480; centrosome-associated protein of 350 kDa; GM133; FLJ38282; FLJ44058; RP11-502H18.1
CEP350 has several biochemical functions, for example, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CEP350 itself. We selected most functions CEP350 had, and list some proteins which have the same functions with CEP350. You can find most of the proteins on our site.
Function microtubule binding
Related Protein GAPDH; MAP1B; CAMSAP2A; GOLGA2; JAKMIP3; JAKMIP1; GLI1; MAP1LC3C; MAP6D1; FTCD
Function protein binding
Related Protein ITM2A; CPSF4; KRT14; PHC2; SRSF10; BIRC7; TRIM3; TCF4; FLI1; MAP3K5
CEP350 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CEP350 here. Most of them are supplied by our site. Hope this information will be useful for your research of CEP350.