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CERS5

  • Official Full Name

    ceramide synthase 5

  • Synonyms

    CERS5; ceramide synthase 5; LAG1 homolog, ceramide synthase 5 , LAG1 longevity assurance homolog 5 (S. cerevisiae) , LASS5; FLJ25304; MGC45411; Trh4; LAG1 homolog, ceramide synthase 5; LAG1 longevity assurance homolog 5; LASS5;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CERS5-1400H Recombinant Human CERS5 Mammalian Cell His
Human CERS5-2659H-B Recombinant Human CERS5 Protein Pre-coupled Magnetic Beads HEK293
Human CERS5-2659H Recombinant Human CERS5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL7254HF Recombinant Full Length Human Ceramide Synthase 5(Cers5) Protein, His-Tagged E.coli expression system His Full Length (1-392)
Mus musculus (Mouse) RFL16061MF Recombinant Full Length Mouse Ceramide Synthase 5(Cers5) Protein, His-Tagged E.coli expression system His Full Length (1-414)
Zebrafish CERS5-10029Z Recombinant Zebrafish CERS5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CERS5 Related Articles

CERS5 involved in several pathways and played different roles in them. We selected most pathways CERS5 participated on our site, such as Metabolic pathways, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with CERS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolic pathwaysCCBL2;TUSC3;GK;MTMR6;UGT1A7C;ALPI.1;ALDH4A1;DTYMK;PYCRL
MetabolismCPNE7;ELA2L;ITPKA;MED20;CSNK1G2;CHST14;ELA2;PDP1;CYP2S1
Metabolism of lipids and lipoproteinsSACM1LA;NEU4;HSD17B11;ARSJ;SCP2B;MED23;GLIPR1;DPEP2;SLC44A5B
Sphingolipid MetabolismGAL3ST1;PPM1LA;ARSE;PPAP2A;ARSF;ACER1;NEU3.5;CERS3B;CERS4A
Sphingolipid de novo biosynthesisVAPB;CERS4A;ACER1;CERS5;COL4A3BP;FA2H;PPM1LA;SGMS2;PPM1LB
Sphingolipid signaling pathwayMAPK3;HRAS;MAPK9;RAC1;PIK3R5;RAC3;PPP2R5E;BID;PIK3R1

CERS5 has several biochemical functions, for example, DNA binding, sphingosine N-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CERS5 itself. We selected most functions CERS5 had, and list some proteins which have the same functions with CERS5. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF287;RYBPB;FOXF2A;ZFP322A;HIST2H2AA4;TSG101;TBX5;ZNF207;HOXC13A
sphingosine N-acyltransferase activityCERS2;FAM57B;CERS3B;CERS5;LASS4;CERS2A;LASS2;CERS4;LASS1

CERS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CERS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CERS5.

Haller, JF; Cavallaro, P; et al. Endogenous beta-glucocerebrosidase activity in Abca12(-/-) epidermis elevates ceramide levels after topical lipid application but does not restore barrier function. JOURNAL OF LIPID RESEARCH 55:493-503(2014).
Kamani, M; Mylvaganam, M; et al. Adamantyl Glycosphingolipids Provide a New Approach to the Selective Regulation of Cellular Glycosphingolipid Metabolism. JOURNAL OF BIOLOGICAL CHEMISTRY 286:21413-21426(2011).
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