CHD8 Protein, chromodomain helicase DNA binding protein 8


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Official Full Name chromodomain helicase DNA binding protein 8
Background CHD8 belongs to the chromodomain helicase DNA-binding (CHD) family of ATP-dependent chromatin remodeling proteins. The CHD family of proteins has been shown to play an important role in regulating gene expression by utilizing the energy derived from ATP h
Synonyms CHD8; chromodomain helicase DNA binding protein 8; helicase with SNF2 domain 1 , HELSNF1; chromodomain-helicase-DNA-binding protein 8; DUPLIN; KIAA1564; axis duplication inhibitor; ATP-dependent helicase CHD8; helicase with SNF2 domain 1; HELSNF1
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHD8-1217H Recombinant Human CHD8 Protein, GST-Tagged Wheat Germ GST
    Mouse CHD8-3383M Recombinant Mouse CHD8 Protein Mammalian Cell His
    Rat CHD8-1366R Recombinant Rat CHD8 Protein Mammalian Cell His
    Zebrafish CHD8-7974Z Recombinant Zebrafish CHD8 Mammalian Cell His

    CHD8 involved in several pathways and played different roles in them. We selected most pathways CHD8 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway FZD9; PLCB4; TRP53; WNT3; RHOAD; PRKACB; RAC1A; PPP3CB; RAC1; AXIN2

    CHD8 has several biochemical functions, for example, ATP binding, DNA binding, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD8 itself. We selected most functions CHD8 had, and list some proteins which have the same functions with CHD8. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding TOR1; ABCD3B; ADCY7; GRK7; ULK1; FDXACB1; ATP7B; KSR1; ETNK2; P2RX1
    DNA helicase activity WRN; PEO1; RECQL5; PIF1; MCM5; RECQL; CHD8; MCM3L; IGHMBP2; DNA2
    DNA-dependent ATPase activity IGHMBP2; TTF2; SMARCA4; SMARCA2; SMARCAL1; MSH6; MSH3; CHD8; XRCC2; RAD51L3
    armadillo repeat domain binding CTNNBIP1; CALCOCO1; STRN4; CHD8; TCF7L2; LEF1; CNOT1; AXIN1; STRN; AXIN2
    beta-catenin binding KLF4; CD2AP; TRPC4; TCF7L1A; TCF7L1B; PTPRJ; DACT2; LZIC; HDAC6; SHROOM2
    chromatin binding BRD3; DNMT1; TRIM37; DNMT3A; RBPJ; RBMX; NEUROD1; MEF2A; Ar; ATAD2
    helicase activity MCM8; SETX; EIF4A1A; DNA2; SHPRH; ACTG2; CHD9; DDX58; ATRX; MOV10B.1
    histone binding HIST1H3I; RNF20; HIST2H3C1; PRMT7; PRKCBP1L; PIH1D1; HIST1H4M; HIST1H47; HIST1H4I; SPTY2D1
    hydrolase activity ABHD14A; PPM1AB; DESI1; HDHD1; BLM; ATP2A1L; URAH; CECR1A; SACM1LB; TENC1
    hydrolase activity, acting on acid anhydrides SMARCA4A; CHD8; CHD9
    methylated histone binding WDR92; PHF13; CBX8; SPIN1; CHD1; ING4; CHD8; PHF1; PHF8; ING2
    nucleotide binding RAC3B; DNAHC8; NAIP7; NMRK2; PDPK1A; NOX4; SRSF1B; ALYREF; ARL15A; KIF5AA
    p53 binding PLK3; PTTG1IP; TRIM24; HTT; BANP; RFWD3; RCHY1; CDKN2AIP; TP73; TP53
    protein binding CYP2S1; FKBP6; VAT1L; TOLLIP; NMRK2; USP28; EGR2; ALS2; CBLL1; NUFIP2

    CHD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD8.


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