CHRNE
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Official Full Name
cholinergic receptor, nicotinic, epsilon
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Overview
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. -
Synonyms
CHRNE; cholinergic receptor, nicotinic, epsilon; cholinergic receptor, nicotinic, epsilon polypeptide; acetylcholine receptor subunit epsilon; ACHRE; ACHE_HUMAN; AchR epsilon subunit; CMS1D; CMS1E; CMS2A; FCCMS; SCCMS;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Xenopus laevis (African clawed frog)
- Zebrafish
- E.coli
- E.coli expression system
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | CHRNE-1293H | Recombinant Human CHRNE Protein, GST-Tagged | Wheat Germ | GST | ||
Human | CHRNE-29131TH | Recombinant Human CHRNE | Wheat Germ | N/A | 110 amino acids | |
Mouse | CHRNE-3442M | Recombinant Mouse CHRNE Protein | Mammalian Cell | His | ||
Mouse | Chrne-7895M | Recombinant Mouse Chrne protein, His & T7-tagged | E.coli | His/T7 | Lys21~Lys239 (Accession # P20782) | |
Mouse | CHRNE-1671M | Recombinant Mouse CHRNE Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | CHRNE-1671M-B | Recombinant Mouse CHRNE Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | Chrne-3057R | Recombinant Rat Chrne, His-tagged | E.Coli or Yeast | His | 494 | |
Rat | CHRNE-1401R | Recombinant Rat CHRNE Protein | Mammalian Cell | His | ||
Rat | CHRNE-1059R-B | Recombinant Rat CHRNE Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | CHRNE-1059R | Recombinant Rat CHRNE Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Bos taurus (Bovine) | RFL872BF | Recombinant Full Length Bovine Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged | E.coli expression system | His | Full Length (21-491) | |
Homo sapiens (Human) | RFL27102HF | Recombinant Full Length Human Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged | E.coli expression system | His | Full Length (21-493) | |
Mus musculus (Mouse) | RFL32653MF | Recombinant Full Length Mouse Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged | E.coli expression system | His | Full Length (21-493) | |
Rattus norvegicus (Rat) | RFL27962RF | Recombinant Full Length Rat Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged | E.coli expression system | His | Full Length (21-494) | |
Xenopus laevis (African clawed frog) | RFL7869XF | Recombinant Full Length Xenopus Laevis Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (20-504) | |
Zebrafish | CHRNE-1106Z | Recombinant Zebrafish CHRNE | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
CHRNE involved in several pathways and played different roles in them. We selected most pathways CHRNE participated on our site, such as Acetylcholine Binding And Downstream Events, Activation of Nicotinic Acetylcholine Receptors, ErbB2/ErbB3 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Acetylcholine Binding And Downstream Events | CHRNA7;CHRNA2;CHRNB4;CHRNA5;CHRND;CHRNA3;CHRNE;CHRNB2;CHRNA4 |
Activation of Nicotinic Acetylcholine Receptors | CHRNA2;CHRNA1;CHRND;CHRNA4;CHRNE;CHRNB2;CHRNB4;CHRNA5;CHRNA7 |
ErbB2/ErbB3 signaling events | RNF41;FMNL3;CHRNA1;DOCK7;CHRNE |
Highly sodium permeable acetylcholine nicotinic receptors | CHRNE;CHRNA3;CHRNB2;CHRNB4;CHRND;CHRNA4 |
Neuroactive ligand-receptor interaction | DRD4B;TAAR64;NMBR;LPAR4;PRSS1;TAAR13D;OPRM1;P2RX7;GPR50 |
Neuronal System | KCNA2;CHRNB2;CHRNA3;KCNQ2A;CHRND;SLC6A11;SLC1A3B;LIN7C;DDX1 |
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | CAMKK1B;NCALDA;NSFB;CHRNA2;CHRNE;CHRND;MYO6;GABRR2A;GRIP1 |
Postsynaptic nicotinic acetylcholine receptors | CHRNE;CHRNA2;CHRND |
CHRNE has several biochemical functions, for example, contributes_to acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNE itself. We selected most functions CHRNE had, and list some proteins which have the same functions with CHRNE. You can find most of the proteins on our site.
Function | Related Protein |
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contributes_to acetylcholine binding | CHRNA9;CHRNA5;CHRNE;CHRNB3B;CHRNA1;CHRNA2A;CHRND;CHRNB3A;CHRNA4B |
acetylcholine receptor activity | CHRNA7;ANXA9;CHRNA5;CHRNB4;CHRNA6;CHRNE;CHRNA4;CHRNA3;CHRNB2 |
acetylcholine-activated cation-selective channel activity | CHRNA10A;CHRNA5;CHRNB3B;CHRNA4;CHRNA6;CHRNB3A;CHRNA2A;CHRNB2;CHRNE |
cation transmembrane transporter activity | SLC41A2;SLC41A1;SLC41A3;SLC30A7;SLC30A9;SLC30A1A;SLC30A1B;SLC30A5;SLC30A10 |
CHRNE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNE here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNE.
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