chsy3
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  • Official Full Name
  • chondroitin sulfate synthase 3
  • Synonyms
  • CHSY3;chondroitin sulfate synthase 3;24293;ENSG00000198108;CSS3;CHSY2;5q23.3;chondroitin sulfate synthase 3;chondroitin sulfate synthase 3;chSy-2;chondroitin synthase 2;chondroitin synthase-2;carbohydrate synthase 2;N-acetylgalactosaminyltransferase 3;chondroitin glucuronyltransferase 3;N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3;glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II;EC 2.4.1.175 EC 2.4.1.226;
Cat.#:CHSY3-11236HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHSY3, His-tagged
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Cat.#:CHSY3-3459MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CHSY3 Protein
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Cat.#:CHSY3-5503ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CHSY3
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Involved Pathway

CHSY3 involved in several pathways and played different roles in them. We selected most pathways CHSY3 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHSY3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
DSE; CHST15; B4GALT7; CHST3B; CHSY3; CHSY1; CHST12A; CHST3; CSGALNACT1; B3GAT3
Metabolic pathways
KDSR; CKBB; ENPP7; ANPEP; ALG12; SCP2; GPAT2; NDUFA4L; ST6GALNAC3; NME3

Protein Function

CHSY3 has several biochemical functions, for example, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHSY3 itself. We selected most functions CHSY3 had, and list some proteins which have the same functions with CHSY3. You can find most of the proteins on our site.
Function
Related Protein
Function N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
Related Protein CHSY1; CHSY3; CHPF; CHPF2
Function glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
Related Protein CHSY3; CHPF; CSGALNACT1; CHSY1
Function metal ion binding
Related Protein ATP2B1; ALOX12E; ATP1A3B; STAMBPA; ZNF438; CACNA2D1; ENDOG; ADI1; Car4; RXRBB

CHSY3 Related Articles

Viola, M; Bartolini, B; et al. Oxidized Low Density Lipoprotein (LDL) Affects Hyaluronan Synthesis in Human Aortic Smooth Muscle Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 288:29595-29603(2013).
Nakagawa, N; Izumikawa, T; et al. Sulfation of glucuronic acid in the linkage tetrasaccharide by HNK-1 sulfotransferase is an inhibitory signal for the expression of a chondroitin sulfate chain on thrombomodulin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 415:109-113(2011).