CIDEA
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Official Full Name
cell death-inducing DFFA-like effector a
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Overview
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. -
Synonyms
CIDEA; cell death-inducing DFFA-like effector a; cell death activator CIDE-A; CIDE A; CIDE-A;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|GST
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CIDEA-1361H | Recombinant Human CIDEA Protein, GST-tagged | Wheat Germ | GST |
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| Human | CIDEA-358HCL | Recombinant Human CIDEA cell lysate | N/A |
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| Human | CIDEA-1834H | Recombinant Human CIDEA protein, His & GST-tagged | E.coli | His/GST | Met1~Gly219 (Accession # O60543) |
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| Human | CIDEA-1848HF | Recombinant Full Length Human CIDEA Protein, GST-tagged | In Vitro Cell Free System | GST | 253 amino acids |
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| Mouse | CIDEA-3471M | Recombinant Mouse CIDEA Protein | Mammalian Cell | His |
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| Mouse | CIDEA-1690M | Recombinant Mouse CIDEA Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | Cidea-789M | Recombinant Mouse Cidea Protein, His-tagged | E.coli | N-His | Met1-Met217 |
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| Mouse | CIDEA-1690M-B | Recombinant Mouse CIDEA Protein Pre-coupled Magnetic Beads | HEK293 |
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| Chicken | CIDEA-4130C | Recombinant Chicken CIDEA | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CIDEA Related Research Area
CIDEA involved in several pathways and played different roles in them. We selected most pathways CIDEA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CIDEA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
CIDEA has several biochemical functions, for example, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CIDEA itself. We selected most functions CIDEA had, and list some proteins which have the same functions with CIDEA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | DMRT2;MID1;NR0B2;BAXA;TPD52;TIGIT;ASGR1;IZUMO1;MAFA |
CIDEA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CIDEA here. Most of them are supplied by our site. Hope this information will be useful for your research of CIDEA.
Dlg4; NR1H2; ZBTB16
- Q&As
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