CISH
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Official Full Name
cytokine inducible SH2-containing protein
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Overview
The suppressor of cytokine signaling (SOCS) family members are negative regulators of cytokine signal transduction that inhibit the Jak/Stat pathway (1-3). The SOCS family consists of at least 8 members including the originally identified cytokine-inducib -
Synonyms
CISH; cytokine inducible SH2-containing protein; cytokine-inducible SH2-containing protein; CIS; CIS 1; G18; SOCS; suppressor of cytokine signaling; cytokine-inducible inhibitor of signaling type 1B; CIS-1; BACTS2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- GST|His
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- CISH Related Articles
CISH involved in several pathways and played different roles in them. We selected most pathways CISH participated on our site, such as Cytokine Signaling in Immune system, EPO Receptor Signaling, Growth hormone receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with CISH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cytokine Signaling in Immune system | NUP35;LAMTOR2;NOD1;IFIT11;IFI6;EDARADD;IFIT14;SPTA1;IFI27 |
EPO Receptor Signaling | CISH;PTPRUB;PTPRU |
Growth hormone receptor signaling | GHRB;CSH1;PRLRB;CSHL1;CISH |
IL-2 Signaling pathway | ITM2BA;CISH;SHB;CD53;NMI |
IL-3 Signaling Pathway | CISH;GATA1;KCNIP3B;BMX;GATA2;BIRC5A;GATA1A;PILRB;GNB2L1 |
IL2-mediated signaling events | DOK2;STAM2;IKZF3;CISH |
Immune System | DEFB119;SIGIRR;ASB17;CD300E;ASB3;DEFA1;TRIM62;S100B;CFHL4 |
Jak-STAT signaling pathway | PTPN2B;IL22RA2;SOS1;IL6R;HRAS;TYK2;SOCS5B;PIK3CD;FHL1A |
CISH has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CISH itself. We selected most functions CISH had, and list some proteins which have the same functions with CISH. You can find most of the proteins on our site.
Function | Related Protein |
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molecular_function | Actl10;CTXN3;MSMB;TP53TG5;PLEKHG3;OLFM3A;TMEM14A;MEOX1;NLRP9C |
protein binding | BBS7;USP36;SDC4;NPM2;RPS14;AP2B1;C1S;ZNF180;DMPK |
CISH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CISH here. Most of them are supplied by our site. Hope this information will be useful for your research of CISH.
EGFR; ERBB2; HSPA6; EPOR; ETV5; MAP3K7CL; SMAD2; Epor; DYNLL1
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