Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

CLCN7

  • Official Full Name

    chloride channel 7

  • Overview

    The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
  • Synonyms

    CLCN7; chloride channel 7; H(+)/Cl(-) exchange transporter 7; CLC 7; CLC7; OPTA2; PPP1R63; protein phosphatase 1; regulatory subunit 63; Chloride channel protein 7; ClC-7; CLCN7_HUMAN; FLJ26686; FLJ39644; FLJ46423; OPTB4; protein phosphatase 1, regulatory subunit 63;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLCN7-11280H Recombinant Human CLCN7, GST-tagged E.coli GST C-term-208a.a.
Human CLCN7-1422H Recombinant Human CLCN7 Protein, GST-tagged Wheat Germ GST
Human CLCN7-7472HCL Recombinant Human CLCN7 293 Cell Lysate HEK293 N/A
Mouse CLCN7-3518M Recombinant Mouse CLCN7 Protein Mammalian Cell His
Mouse CLCN7-1722M Recombinant Mouse CLCN7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CLCN7-1722M-B Recombinant Mouse CLCN7 Protein Pre-coupled Magnetic Beads HEK293
Rat CLCN7-1428R Recombinant Rat CLCN7 Protein Mammalian Cell His
Rat CLCN7-1086R-B Recombinant Rat CLCN7 Protein Pre-coupled Magnetic Beads HEK293
Rat CLCN7-1086R Recombinant Rat CLCN7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CLCN7-4750Z Recombinant Zebrafish CLCN7 Mammalian Cell His
Chicken CLCN7-2351C Recombinant Chicken CLCN7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CLCN7 involved in several pathways and played different roles in them. We selected most pathways CLCN7 participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLCN7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ion channel transportSGK2;TRPC4;TRPM6;ATP2B1B;TRPC4A;TTYH3B;TRPV3;TRPM1;UNC79
Stimuli-sensing channelsFKBP1B;WNK2;TRPC4AP;BSND;CLCN2;TRPC5A;TPCN1;ANO10;TRPM1A
Transmembrane transport of small moleculesSLC26A3.1;WNK2;TRPA1B;SLC28A1;SLC6A18;SLC7A11;TRPM4A;SLC29A3;SLC22A7B.1

CLCN7 has several biochemical functions, for example, ATP binding, antiporter activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLCN7 itself. We selected most functions CLCN7 had, and list some proteins which have the same functions with CLCN7. You can find most of the proteins on our site.

Function Related Protein
ATP bindingAGK;JAK1;RFK;ATP6V1AA;GK5;CMPK2;ATP2B3B;CSNK2A2A;PSMC6
antiporter activitySLC7A5;CLCN4-2;SLC24A4;SLC35D1A;CLCN3;SLC35C2;SLC47A1;TMCO3;CLCN6
chloride channel activityCLIC3;CLCA2;SLC26A1;CLIC5B;GABRR1;TTYH3B;CLCN3;SLC26A9;GABRB2
voltage-gated chloride channel activityCLCNKB;CLCNK;CLCN1;ANO6;CLCNKA;CLCN7;CLCN1A;CLCN4;CLCN5

CLCN7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLCN7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLCN7.

CREB3; pi3p; Ktn1; SLC33A1; Kcnk1; Flot1; XRCC3; Atp2a2; ATP6AP2; Rab5c; Bmpr1a; RAB5C; TMEM63B; Nup98; SAMD1; C1qbp; FAM46A; Vps28; Cd2ap; Tmed2

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All CLCN7 Products

Required fields are marked with *

My Review for All CLCN7 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends