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CLNK

Official Full Name

cytokine-dependent hematopoietic cell linker
Overview

MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the;regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR);signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 (PubMed;10562326); Goitsuka et al., 2000, 2001 (PubMed 10744659) (PubMed 11463797)).
Synonyms

CLNK; cytokine-dependent hematopoietic cell linker; mast cell immunoreceptor signal transducer; MIST; MGC35197;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CLNK-1508H	Recombinant Human CLNK Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CLNK-1884HF	Recombinant Full Length Human CLNK Protein, GST-tagged	In Vitro Cell Free System	GST	428 amino acids	Inquiry
Human	CLNK-3251H	Recombinant Human CLNK Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Mouse	CLNK-3594M	Recombinant Mouse CLNK Protein	Mammalian Cell	His		Inquiry
Mouse	Clnk-2195M	Recombinant Mouse Clnk Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	CLNK-1764M-B	Recombinant Mouse CLNK Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	CLNK-1764M	Recombinant Mouse CLNK Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CLNK involved in several pathways and played different roles in them. We selected most pathways CLNK participated on our site, such as XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLNK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
XPodNet - protein-protein interactions in the podocyte expanded by STRING	Siglece;CARF;GIMAP3;MTAP1A;WLS;KCP;SNTB1;GAB3;ZFP423

CLNK has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLNK itself. We selected most functions CLNK had, and list some proteins which have the same functions with CLNK. You can find most of the proteins on our site.

Function	Related Protein
protein binding	GPX3;SOSTDC1B;SETDB1;POU3F2;THG1L;POLM;NTM;ZNF707;R3HDM2

CLNK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLNK here. Most of them are supplied by our site. Hope this information will be useful for your research of CLNK.

Fyb; Fgr; Lyn; Fyn; Skap2; Skap1