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COG4

  • Official Full Name

    component of oligomeric golgi complex 4

  • Overview

    The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    COG4; component of oligomeric golgi complex 4; conserved oligomeric Golgi complex subunit 4; COD1; DKFZP586E1519; COG 4; COG complex subunit 4; Complexed with Dor1p; Conserved oligomeric Golgi complex protein 4; CDG2J;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COG4-27221TH Recombinant Human COG4, His-tagged E.coli His
Human COG4-1626H Recombinant Human COG4 Protein, GST-tagged Wheat Germ GST
Human COG4-2082HF Recombinant Full Length Human COG4 Protein, GST-tagged In Vitro Cell Free System GST 785 amino acids
Zebrafish COG4-3663Z Recombinant Zebrafish COG4 Mammalian Cell His
Chicken COG4-2004C Recombinant Chicken COG4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • COG4 Related Articles

COG4 involved in several pathways and played different roles in them. We selected most pathways COG4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with COG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

COG4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COG4 itself. We selected most functions COG4 had, and list some proteins which have the same functions with COG4. You can find most of the proteins on our site.

Function Related Protein
protein bindingSOX10;SPG21;JAM3B;PRX;KATNBL1;GDF2;FURIN;INPP5A;C10orf62

COG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of COG4.

SCFD1; COG7; STX5; COG2; COG1

Gremillion, SK; Harris, SD; et al. Mutations in proteins of the Conserved Oligomeric Golgi Complex affect polarity, cell wall structure, and glycosylation in the filamentous fungus Aspergillus nidulans. FUNGAL GENETICS AND BIOLOGY 73:69-82(2014).
Ha, JY; Pokrovskaya, ID; et al. Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:15762-15767(2014).
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