COL3A1

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COL3A1

Official Full Name collagen, type III, alpha 1
Background This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Synonyms COL3A1; collagen, type III, alpha 1; EDS4A; collagen alpha-1(III) chain; collagen, fetal; alpha1 (III) collagen; Ehlers-Danlos syndrome type IV, autosomal dominant;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Placenta
    • Mammalian Cell
    • NS0
    • P.pastoris
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL3A1-001H Native Human COL3A1 Protein Human Placenta
    Human COL3A1-5149H Recombinant Human COL3A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human COL3A1-1650H Recombinant Human COL3A1 Protein, GST-tagged Wheat Germ GST
    Human COL3A1-1957H Recombinant Human Collagen, Type III, Alpha 1 P.pastoris N/A
    Human COL3A1-19587H Recombinant Human COL3A1 protein P.pastoris N/A
    Human COL3A1-28012TH Recombinant Human COL3A1 N/A
    Human COL3A1-3440H Recombinant Human COL3A1 Protein, His-tagged Yeast His
    Human COL3A1-604H Recombinant Human COL3A1, His-tagged NS0 His
    Human COL3A1-72H Recombinant Human COL3A1 E.coli N/A
    Human COL3A1-73H Recombinant Human COL3A1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human COL3A1-7927H Recombinant Human COL3A1 protein, His & GST-tagged E.coli His/GST
    Mouse COL3A1-09M Recombinant Mouse Col3a1 protein, His-tagged HEK293 His
    Mouse COL3A1-3734M Recombinant Mouse COL3A1 Protein Mammalian Cell His
    Mouse Col3a1-7928M Recombinant Mouse Col3a1 protein, His-tagged E.coli His
    Rat COL3A1-1522R Recombinant Rat COL3A1 Protein Mammalian Cell His
    Rat Col3a1-7929R Recombinant Rat Col3a1 protein, His-tagged E.coli His
    Rhesus Macaque COL3A1-961R Recombinant Rhesus monkey COL3A1 Protein, His-tagged Mammalian Cell His
    Chicken COL3A1-6932C Recombinant Chicken COL3A1 Mammalian Cell His

    COL3A1 involved in several pathways and played different roles in them. We selected most pathways COL3A1 participated on our site, such as Amoebiasis, Assembly of collagen fibrils and other multimeric structures, Binding and Uptake of Ligands by Scavenger Receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL3A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amoebiasis IL12B; PRKACG; LAMC2; COL27A1; IL1B; ARG1; PRKCG; ADCY1; IL6; COL5A1
    Assembly of collagen fibrils and other multimeric structures COL4A6; BMP1; COL8A2; COL5A3B; COL6A1; CTSB; COL5A2; COL4A3; CD151; LOXL2
    Binding and Uptake of Ligands by Scavenger Receptors SPARC; NFX1; HYOU1; APOBB.1; COL3A1; IGKV1-5; HSPH1; SCGB3A2; COL1A2; Alb
    Collagen biosynthesis and modifying enzymes COL10A1; COL9A1A; COL10A1A; COL5A2; COL8A2; SERPINH1A; COL5A3A; SERPINH1; COL4A3; COL23A1
    Collagen formation PCOLCEB; COL19A1; COL17A1A; COL5A1; TLDC2; COL16A1; COL28A1; BMP1A; SERPINH1B; ABHD1
    ECM-receptor interaction LAMA2; SV2B; LAMA1; LAMA3; COL1A1A; ITGAV; COL6A1; SV2A; ITGA7; TNN
    Endothelins EDNRB; EDNRA; COL3A1; EDN3; EDN2; EDN1; COL1A2; CYSLTR1
    Extracellular matrix organization MFAP3; MMP17; MFAP5; LOC100686744; LTBP3; ELANE; ADAMTS2; MMP24; EFEMP1; LEPREL2

    COL3A1 has several biochemical functions, for example, SMAD binding, extracellular matrix structural constituent, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL3A1 itself. We selected most functions COL3A1 had, and list some proteins which have the same functions with COL3A1. You can find most of the proteins on our site.

    Function Related Protein
    SMAD binding SKOR2; FKBP1A; SKIB; BMP2; YY1; BMPR1A; TGFBR1; SKOR1B; RNF111; EP300
    extracellular matrix structural constituent EFEMP2; COL24A1; MATN3; COL27A1A; ELNA; COL4A6; TFPI2; BGN; COL8A2; COL3A1
    integrin binding CTGFB; P4HB; ADAM9; ANGPTL3; TLN1; ANXA7; SFRP2; ITGB1BP1; AMICA1; TSPAN4
    metal ion binding GALNTL1; ZNF165; ARSK; MCCC1; ARHGAP29; PPP4C; TRIM35-21; POLH; AMY1A; PTS
    platelet-derived growth factor binding COL5A1; PDGFRA; PDGFRB; COL3A1; COL4A1; PDGFB; PDGFA; COL1A1; COL2A1; COL6A1
    protein binding EIF4A3; EFNA3; RQCD1; CCND1; MT3; GOLSYN; SMAD9; NDFIP2; CNBP; FGF7

    COL3A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL3A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL3A1.

    all3_aedae; zwf; LOX; ispH; lcrS; pdpD2; q5nfa1_fratt; galT; pbpG; htrE; nagE; opuD; mutTA; thiF; katB; rpoB; q81vw1_bacan; q8ckb2_yerpe; mutY

    Vittal, R; Mickler, EA; et al. Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-beta and Associated Transcripts in Pulmonary Fibrosis. PLOS ONE 8:-(2013).
    Hung, CF; Rohani, MG; et al. Role of IGF-1 pathway in lung fibroblast activation. RESPIRATORY RESEARCH 14:-(2013).

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