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CPSF1

  • Official Full Name

    cleavage and polyadenylation specific factor 1, 160kDa

  • Overview

    Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime;processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to;facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and;Manley, 1995 (PubMed 7590244)).
  • Synonyms

    CPSF1; cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specific factor 1, 160kD subunit; cleavage and polyadenylation specificity factor subunit 1; Cleavage and polyadenylation specificity factor 160 kDa subunit; CPSF 160 kDa subunit; CPSF160; HSU37012; P/cl.18; polyadenylation specificity factor;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CPSF1-1667H Recombinant Human CPSF1 protein, His & T7-tagged E.coli His/T7 Met1~Leu300 (Accession # Q10570)
Mouse CPSF1-3858M Recombinant Mouse CPSF1 Protein Mammalian Cell His
Mouse CPSF1-1942M Recombinant Mouse CPSF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CPSF1-1942M-B Recombinant Mouse CPSF1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CPSF1-1008R Recombinant Rhesus monkey CPSF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CPSF1-833R-B Recombinant Rhesus Macaque CPSF1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CPSF1-833R Recombinant Rhesus Macaque CPSF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CPSF1-6460Z Recombinant Zebrafish CPSF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CPSF1 involved in several pathways and played different roles in them. We selected most pathways CPSF1 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA surveillance pathwayCPSF6;NCBP1;PPP2R5E;RBM8A;WDR33;PPP2R5D;WDR82;CASC3;PPP1CB

CPSF1 has several biochemical functions, for example, RNA binding, enzyme binding, mRNA 3-UTR AU-rich region binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPSF1 itself. We selected most functions CPSF1 had, and list some proteins which have the same functions with CPSF1. You can find most of the proteins on our site.

Function Related Protein
RNA bindingOOEP;EIF2S1B;U2AF2A;XPO1;ZNF239;PAPOLA;IGF2BP2A;RPL3;A1CF
enzyme bindingKALRN;PHKG1;UGT1A1;PRKCE;ITGB3;HDAC1;PCBP2;MAP2K7;ZFP36
mRNA 3-UTR AU-rich region bindingCPEB1;ELAVL1;CPEB3;CPEB1B;ZFP36;CPEB2;CPSF1
nucleic acid bindingCCDC75;ZFP12;RBM39B;JRKL;ZNF747;ZNF367;WT1B;KLF2B;ENOX1

CPSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPSF1.

Ywhae

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