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CPT2

  • Official Full Name

    carnitine palmitoyltransferase 2

  • Overview

    The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
  • Synonyms

    CPT2; carnitine palmitoyltransferase 2; carnitine palmitoyltransferase II , CPT1; carnitine O-palmitoyltransferase 2, mitochondrial; CPTASE; mitochondrial; Carnitine O palmitoyltransferase 2; Carnitine O palmitoyltransferase 2 mitochondrial; Carnitine O-palmitoyltransferase 2; Carnitine palmitoyltransferase II; CPT 1; CPT 2; CPT II; CPT1; CPT2_HUMAN; CPTII; MS722; OTTHUMP00000010493; IIAE4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CPT2-26983TH Recombinant Human CPT2 Wheat Germ N/A 100 amino acids
Human CPT2-1821H Recombinant Human CPT2 Protein, GST-tagged Wheat Germ GST
Human CPT2-391H Recombinant Human CPT2 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CPT2-391HCL Recombinant Human CPT2 cell lysate N/A
Human CPT2-4366HFL Recombinant Full Length Human CPT2 protein, Flag-tagged Mamanlian cells Flag
Human CPT2-5788H Recombinant Human CPT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CPT2-652H Recombinant Human CPT2 Protein, His/GST-tagged E.coli His/GST Ala152~Ser658
Human CPT2-2233HF Recombinant Full Length Human CPT2 Protein, GST-tagged In Vitro Cell Free System GST 658 amino acids
Mouse CPT2-3868M Recombinant Mouse CPT2 Protein Mammalian Cell His
Mouse CPT2-1949M Recombinant Mouse CPT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CPT2-1949M-B Recombinant Mouse CPT2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cpt2-937M Recombinant Mouse Cpt2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CPT2-1579R Recombinant Rat CPT2 Protein Mammalian Cell His
Rat CPT2-1236R Recombinant Rat CPT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CPT2-1236R-B Recombinant Rat CPT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CPT2-1012R Recombinant Rhesus monkey CPT2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CPT2-837R Recombinant Rhesus Macaque CPT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CPT2-837R-B Recombinant Rhesus Macaque CPT2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CPT2-1823Z Recombinant Zebrafish CPT2 Mammalian Cell His
Chicken CPT2-2943C Recombinant Chicken CPT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CPT2 Related Articles

CPT2 involved in several pathways and played different roles in them. We selected most pathways CPT2 participated on our site, such as Fatty Acid Beta Oxidation, Fatty acid degradation, Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fatty Acid Beta OxidationCPT2;ECI1;SLC25A20;CHKB;CRAT;DECR1;CPT1B;CPT1A
Fatty acid degradationACADSB;CPT2;ALDH3A2A;ACADM;ACSL4B;CPT1C;ADH7;ACADVL;ACAA1
Fatty acid metabolismACAA1;ACSL3A;ACADM;ACSL4;FADS2;TECR;MECR;ACOX3;PTPLAD2
Fatty acid, triacylglycerol, and ketone body metabolismDGAT1B;PLIN2;MMAA;THEM5;CYP4A11;ANKRD1;ACOT13;MED19;CYP7A1
Import of palmitoyl-CoA into the mitochondrial matrixCPT2;SLC25A20
MetabolismCOX14;NFYBA;TCN1;CKMT2;SACM1L;DPYD;SLC25A13;SCP2B;CHAT
Metabolism of lipids and lipoproteinsMED26;ARSH;ARSF;ACOT11A;NFYAL;ARSD;MTP;CPTP;CYP4T8
Mitochondrial LC-Fatty Acid Beta-OxidationSLC25A20;EHHADH;ECI1;CPT2

CPT2 has several biochemical functions, for example, carnitine O-palmitoyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CPT2 itself. We selected most functions CPT2 had, and list some proteins which have the same functions with CPT2. You can find most of the proteins on our site.

Function Related Protein
carnitine O-palmitoyltransferase activityCPT1A;CPT1B;CPT1C;CPT2

CPT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPT2.

ICT1; P

Lavarias, S; Pasquevich, MY; et al. Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 152:364-369(2009).
Fukumoto, K; Pierro, A; et al. Tyrosine nitration of carnitine palmitoyl transferase I during endotoxaemia in suckling rats. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1683:1-6(2004).
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