crb3
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  • Official Full Name
  • crumbs homolog 3 (Drosophila)
  • Background
  • This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Synonyms
  • CRB3; crumbs homolog 3 (Drosophila); crumbs protein homolog 3; MGC17303
Cat.#:CRB3-1836HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CRB3 Protein, GST-tagged
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Cat.#:CRB3-11555HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRB3, GST-tagged
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Cat.#:CRB3-3882MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CRB3 Protein
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Cat.#:CRB3-1017RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CRB3 Protein, His-tagged
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Cat.#:CRB3-394HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CRB3 cell lysate
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Involved Pathway

CRB3 involved in several pathways and played different roles in them. We selected most pathways CRB3 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRB3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Tight junction
MYL5; MYL12.1; LLGL2; EPB41L3B; MYL7; MYL9B; PPP2R2BB; CLDN16; MYL9A; GNAI2

Protein Function

CRB3 has several biochemical functions, for example, SH3 domain binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRB3 itself. We selected most functions CRB3 had, and list some proteins which have the same functions with CRB3. You can find most of the proteins on our site.
Function
Related Protein
Function SH3 domain binding
Related Protein LANCL1; PDCD6IP; GRIK5; ITM2B; MICAL1; PLSCR3; ELMO3; EFS; ZFP106; FUT8
Function protein binding
Related Protein CCNE1; TFRC; KLRD1; BCL11B; AFG3L2; SYT17; ASF1A; SLC4A4; RNMT; SPSB1
Function protein domain specific binding
Related Protein THRA; XPO1; VAPA; HIST1H4E; TRIM11; YWHAH; HIST2H4A; ACSL3; MED12; CALM3

Interacting Protein

CRB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRB3.
PSMA3; RAB11FIP5