CRB3
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Official Full Name
crumbs homolog 3 (Drosophila)
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Overview
This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. -
Synonyms
CRB3; crumbs homolog 3 (Drosophila); crumbs protein homolog 3; MGC17303;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
CRB3 involved in several pathways and played different roles in them. We selected most pathways CRB3 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | CLDN2;TJAP1;RAB13;CLDN7;PRKCB;SPTAN1;HRASA;RHOAD;GNAI3 |
CRB3 has several biochemical functions, for example, SH3 domain binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRB3 itself. We selected most functions CRB3 had, and list some proteins which have the same functions with CRB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3 domain binding | KHDRBS1;RAD9A;SHANK3;PTTG2;INPPL1;PTTG1;GRIK5;SH3BGR;SH3BP5LA |
| protein binding | VENTX;SHPRH;CIB1;NAT8B;NISCH;ZZZ3;ZNF193;B9D2;VPS4B |
| protein domain specific binding | STX18;ATP1A1;SHROOM2;CNTROB;YWHABA;GABRR2;DYNLL1;SNCA;GABRR1 |
CRB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRB3.
PSMA3; RAB11FIP5
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