CSRP3
-
Official Full Name
cysteine and glycine-rich protein 3 (cardiac LIM protein)
-
Overview
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene. This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. -
Synonyms
CSRP3; cysteine and glycine-rich protein 3 (cardiac LIM protein); cysteine and glycine-rich protein 3; CLP; CMD1M; MLP; cardiac; Muscle LIM protein; Cardiac LIM protein; CRP3; CSRP3_HUMAN; Cysteine rich protein 3; Cysteine-rich protein 3; LIM domain only 4; LIM domain protein; LMO4; OTTHUMP00000235874; cardiac LIM domain protein; LIM domain protein, cardiac; CMH12; MGC14488; MGC61993;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
CSRP3 involved in several pathways and played different roles in them. We selected most pathways CSRP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CSRP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
CSRP3 has several biochemical functions, for example, actinin binding, protein binding, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by CSRP3 itself. We selected most functions CSRP3 had, and list some proteins which have the same functions with CSRP3. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
actinin binding | RELA;MICALL2;PROM1;PDLIM5;NFKB1;PKD2;TTN;CSRP3 |
protein binding | SDHB;PVRL2;UBQLN1;CCL11;SDCBP;P4HA1;SULT1A3;CCDC93;CHDH |
structural constituent of muscle | ACTN3;MYBPC1;MYBPC2;TPM4;OBSCN;JPH1;ANKRD2;MYL9;SORBS2 |
telethonin binding | BMP10;MYOZ2;CSRP3;KCNE1;TTN |
zinc ion binding | ZKSCAN5;TP53I3;PDLIM1;ESRRB;LMO2;PAPPA;ZDHHC6;BTR09;S100A6 |
CSRP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSRP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSRP3.
TCAP; MYOD1; MYOG; CFL2; s4s7m7_human; LIMS1; FHL1; RIN3; ACTN2
- Q&As
- Reviews
Q&As (5)
Ask a questionThere is emerging interest in exploring the potential of CSRP3 in regenerative medicine, particularly in the context of muscle regeneration and repair.
Potential therapeutic strategies may involve gene therapy, small molecule inhibitors, or other approaches aimed at modulating the function of CSRP3.
Genetic variations in the CSRP3 gene have been linked to certain cardiac and muscular disorders, providing insights into disease susceptibility.
CSRP3 has been implicated in skeletal muscle disorders, such as muscular dystrophy, suggesting its relevance in potential therapeutic interventions.
One challenge is understanding the precise mechanisms by which CSRP3 contributes to disease pathogenesis and how best to modulate its function.
Customer Reviews (3)
Write a reviewThe CSRP3 Protein comes highly recommended for its exceptional performance, particularly in ELISA assays.
Researchers utilizing the CSRP3 Protein can rely on its robust and reproducible performance in a variety of experimental settings.
This protein has proven to be of great utility in protein electron microscopy structure analysis.
Ask a Question for All CSRP3 Products
Required fields are marked with *
My Review for All CSRP3 Products
Required fields are marked with *