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CSRP3

  • Official Full Name

    cysteine and glycine-rich protein 3 (cardiac LIM protein)

  • Overview

    This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene. This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
  • Synonyms

    CSRP3; cysteine and glycine-rich protein 3 (cardiac LIM protein); cysteine and glycine-rich protein 3; CLP; CMD1M; MLP; cardiac; Muscle LIM protein; Cardiac LIM protein; CRP3; CSRP3_HUMAN; Cysteine rich protein 3; Cysteine-rich protein 3; LIM domain only 4; LIM domain protein; LMO4; OTTHUMP00000235874; cardiac LIM domain protein; LIM domain protein, cardiac; CMH12; MGC14488; MGC61993;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CSRP3-26431TH Recombinant Human CSRP3, T7 -tagged E.coli T7
Human CSRP3-3055H Recombinant Human CSRP3 protein, His-sumo-tagged E.coli His/SUMO aa 1-194
Human CSRP3-3053H Recombinant Human CSRP3 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CSRP3-2021H Recombinant Human CSRP3 Protein, GST-tagged Wheat Germ GST
Human CSRP3-3050H Recombinant Human CSRP3, T7-tagged E.coli T7
Human CSRP3-7229HCL Recombinant Human CSRP3 293 Cell Lysate HEK293 N/A
Human CSRP3-021H Recombinant Human CSRP3 protein, GST-tagged E. coli GST 1-194 aa
Human CSRP3-7268HFL Recombinant Full Length Human CSRP3 protein, Flag-tagged Mamanlian cells Flag
Human CSRP3-2230HF Recombinant Full Length Human CSRP3 Protein, GST-tagged In Vitro Cell Free System GST 194 amino acids
Mouse CSRP3-3992M Recombinant Mouse CSRP3 Protein Mammalian Cell His
Mouse CSRP3-2032M-B Recombinant Mouse CSRP3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Csrp3-2345M Recombinant Mouse Csrp3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CSRP3-2032M Recombinant Mouse CSRP3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CSRP3-1642R Recombinant Rat CSRP3 Protein Mammalian Cell His
Rat CSRP3-1300R-B Recombinant Rat CSRP3 Protein Pre-coupled Magnetic Beads HEK293
Rat CSRP3-1300R Recombinant Rat CSRP3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CSRP3-1541Z Recombinant Zebrafish CSRP3 Mammalian Cell His
Chicken CSRP3-4337C Recombinant Chicken CSRP3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CSRP3 involved in several pathways and played different roles in them. We selected most pathways CSRP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CSRP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CSRP3 has several biochemical functions, for example, actinin binding, protein binding, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by CSRP3 itself. We selected most functions CSRP3 had, and list some proteins which have the same functions with CSRP3. You can find most of the proteins on our site.

Function Related Protein
actinin bindingRELA;MICALL2;PROM1;PDLIM5;NFKB1;PKD2;TTN;CSRP3
protein bindingSDHB;PVRL2;UBQLN1;CCL11;SDCBP;P4HA1;SULT1A3;CCDC93;CHDH
structural constituent of muscleACTN3;MYBPC1;MYBPC2;TPM4;OBSCN;JPH1;ANKRD2;MYL9;SORBS2
telethonin bindingBMP10;MYOZ2;CSRP3;KCNE1;TTN
zinc ion bindingZKSCAN5;TP53I3;PDLIM1;ESRRB;LMO2;PAPPA;ZDHHC6;BTR09;S100A6

CSRP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSRP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSRP3.

TCAP; MYOD1; MYOG; CFL2; s4s7m7_human; LIMS1; FHL1; RIN3; ACTN2

  • Q&As
  • Reviews

Q&As (5)

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Can CSRP3 protein be used in regenerative medicine applications? 01/13/2023

There is emerging interest in exploring the potential of CSRP3 in regenerative medicine, particularly in the context of muscle regeneration and repair.

What potential therapeutic strategies involve targeting CSRP3 protein? 05/18/2021

Potential therapeutic strategies may involve gene therapy, small molecule inhibitors, or other approaches aimed at modulating the function of CSRP3.

Are there any genetic variations in the CSRP3 gene associated with disease susceptibility? 06/21/2019

Genetic variations in the CSRP3 gene have been linked to certain cardiac and muscular disorders, providing insights into disease susceptibility.

How does CSRP3 protein relate to skeletal muscle diseases? 11/26/2018

CSRP3 has been implicated in skeletal muscle disorders, such as muscular dystrophy, suggesting its relevance in potential therapeutic interventions.

Are there any challenges in targeting CSRP3 for clinical applications? 05/27/2017

One challenge is understanding the precise mechanisms by which CSRP3 contributes to disease pathogenesis and how best to modulate its function.

Customer Reviews (3)

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Reviews
12/23/2022

    The CSRP3 Protein comes highly recommended for its exceptional performance, particularly in ELISA assays.

    01/06/2021

      Researchers utilizing the CSRP3 Protein can rely on its robust and reproducible performance in a variety of experimental settings.

      05/18/2017

        This protein has proven to be of great utility in protein electron microscopy structure analysis.

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