Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

CTCFL

Official Full Name

CCCTC-binding factor (zinc finger protein)-like
Overview

CCCTC-binding factor (CTCF) and its paralog, the Brother of the Regulator of Imprinted Sites (BORIS), are highly conserved transcription factors that regulate transcriptional activation and repression, insulator function, and imprinting control regions (I
Synonyms

CTCFL; CCCTC-binding factor (zinc finger protein)-like; transcriptional repressor CTCFL; BORIS; cancer/testis antigen 27; CT27; dJ579F20.2; HMG-1L1; CTCF paralog; CTCF-like protein; BORIS-like protein; zinc finger protein CTCF-T; brother of the regulator;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ
Yeast

Tag

GST
His
His (Fc)
Avi
His|SUMO
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CTCFL-27664TH	Recombinant Human CTCFL	Wheat Germ	N/A	101 amino acids	Inquiry
Human	CTCFL-2058H	Recombinant Human CTCFL Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CTCFL-7212HCL	Recombinant Human CTCFL 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	CTCFL-4014M	Recombinant Mouse CTCFL Protein	Mammalian Cell	His		Inquiry
Mouse	CTCFL-434M	Recombinant Mouse CTCFL Protein (1-636 aa), His-SUMO-tagged	E.coli	His/SUMO	1-636 aa	Inquiry
Mouse	CTCFL-2044M	Recombinant Mouse CTCFL Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CTCFL-2044M-B	Recombinant Mouse CTCFL Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	CTCFL-1372M	Recombinant Mouse CTCFL Protein (1-636 aa), His-tagged	Yeast	His	1-636 aa	Inquiry

Involved Pathway
Protein Function
Interacting Protein
CTCFL Related Articles

CTCFL involved in several pathways and played different roles in them. We selected most pathways CTCFL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CTCFL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CTCFL has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTCFL itself. We selected most functions CTCFL had, and list some proteins which have the same functions with CTCFL. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	SIM1;PCBP2;MSXC;ZNF189;ZNF507;NR1D2A;JRK;VENT;NEUROG1
RNA polymerase II core promoter proximal region sequence-specific DNA binding	POU2F3;FIGLA;ZNF114;GABPA;T;PAX8;PRDM1;NPAS4;NKX6-2
histone binding	AIRE;TONSL;HIST1H4L;HIST1H4I;LEF1;DTX3L;HIST1H3G;TBL1X;SERPINB1A
metal ion binding	NDUFS8;NT5DC1;NR6A1B;CSGALNACT1;LTN1;NCS1A;CDH24;TDO2A;ZSWIM4
protein binding	MRPS31;MRE11A;FCRL4;CYP4F2;MUL1;ANGPTL4;MIPOL1;NFKBID;ARAP1
sequence-specific DNA binding	KLF2;FOSL1A;RARAB;NR5A2;SOX2;HOXA11;LBX1;HOXC13;POU1F1
transcription regulatory region DNA binding	NKX3-1;CTCFL;ERBB4;LEF1;ZFP513;ZFP335;WNT5A;SOX5;ZFP821
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	HNRNPK;TCF12;NR4A2;CAMTA2;RAX;ZFP750;NKX2-8;HOXD13;NKX2-5

CTCFL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTCFL here. Most of them are supplied by our site. Hope this information will be useful for your research of CTCFL.

b4dyc6_human; SGTA; STIP1; FKBP5; q53fc7_human; HSP90AB1; NUDCD3; UNC45B; NUDCD2; q96be0_human; AARSD1; q9hav2_human; STUB1; NUDC; ZDHHC17

Hoivik, EA; Kusonmano, K; et al. Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene. ONCOTARGET 5:1052-1061(2014).

Nikolic, T; Movita, D; et al. The DNA-binding factor Ctcf critically controls gene expression in macrophages. CELLULAR & MOLECULAR IMMUNOLOGY 11:58-70(2014).