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CXXC1

  • Official Full Name

    CXXC finger protein 1

  • Overview

    Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate;gene expression (Carlone and Skalnik, 2001 (PubMed 11604496)).
  • Synonyms

    CXXC1; CXXC finger protein 1; CXXC finger 1 (PHD domain); cpG-binding protein; CFP1; CGBP; CpG binding protein; DNA binding protein with PHD finger and CXXC domain; hCGBP; HsT2645; PCCX1; PHF18; SPP1; ZCGPC1; zinc finger; CpG binding type containing 1; CX;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CXXC1-2204H Recombinant Human CXXC1 Protein, GST-tagged Wheat Germ GST
Human CXXC1-27242TH Recombinant Human CXXC1, His-tagged E.coli His
Human CXXC1-7151HCL Recombinant Human CXXC1 293 Cell Lysate HEK293 N/A
Human CXXC1-3305H Recombinant Human CXXC1 protein, His-tagged E.coli His
Human CXXC1-2372HF Recombinant Full Length Human CXXC1 Protein, GST-tagged In Vitro Cell Free System GST 656 amino acids
Rhesus Macaque CXXC1-1118R Recombinant Rhesus monkey CXXC1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CXXC1-943R Recombinant Rhesus Macaque CXXC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CXXC1-943R-B Recombinant Rhesus Macaque CXXC1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CXXC1 involved in several pathways and played different roles in them. We selected most pathways CXXC1 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with CXXC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
IRE1alpha activates chaperonesSEC63;HYOU1;PDIA6;FKBP14;SEC61B;CXXC1;C19orf10;PREB;DDX11
Metabolism of proteinsTIMM17B;CGB5;MPDU1;TRAPPC9;TBCD;SERPINA7;PMPCB;EEF1G;KCNA6
Unfolded Protein Response (UPR)HDGF;YIF1A;YY2;TPP1;CTDSP2;WIPI1;DDX11;HYOU1;C19orf10
XBP1(S) activates chaperone genesDDX11;DNAJB9;WIPI1;SEC63;KLHDC3;PDIA6;KDELR3;YIF1A;HDGF

CXXC1 has several biochemical functions, for example, core promoter proximal region sequence-specific DNA binding, contributes_to histone methyltransferase activity (H3-K4 specific), protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXXC1 itself. We selected most functions CXXC1 had, and list some proteins which have the same functions with CXXC1. You can find most of the proteins on our site.

Function Related Protein
core promoter proximal region sequence-specific DNA bindingZFP516;SMAD3;CREBBP;KLF1;DMRTA1;SMAD4;DMRTC1C2;DMRT2;PAX2
contributes_to histone methyltransferase activity (H3-K4 specific)CXXC1;DYDC2;RBBP5;DYDC1;DPY30;ASH2L
protein bindingATF4;SIT1;RECQL4;GSG2;MPDU1;SPOPL;RAB38;ELN;SHFM1
unmethylated CpG bindingMLL1;CXXC1;DNMT3B;KDM2A;DNMT3A
zinc ion bindingSIVA1;FBXO30A;Ar;ZFML;MSL2B;TK1;TRIM8;CA5;USP45

CXXC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXXC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXXC1.

RBBP5; SETD1A; TP53; WDR5

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