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CYFIP1

Official Full Name

cytoplasmic FMR1 interacting protein 1
Overview

Cytoplasmic FMR1-interacting protein 1 is a protein that in humans is encoded by the CYFIP1 gene.
Synonyms

CYFIP1; cytoplasmic FMR1 interacting protein 1; cytoplasmic FMR1-interacting protein 1; cytoplasmic FMRP interacting protein 1; KIAA0068; P140SRA 1; selective hybridizing clone; SHYC; CY; CYFP1_HUMAN; p140sra-1; P140SRA1; Specifically Rac1 associated protein 1; Specifically Rac1-associated protein 1; SRA 1; Sra-1; SRA1;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	CYFIP1-2228H	Recombinant Human CYFIP1 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Mouse	CYFIP1-4137M	Recombinant Mouse CYFIP1 Protein	Mammalian Cell	His	Inquiry
Mouse	CYFIP1-2121M	Recombinant Mouse CYFIP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	CYFIP1-2121M-B	Recombinant Mouse CYFIP1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	CYFIP1-12029Z	Recombinant Zebrafish CYFIP1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
CYFIP1 Related Articles

CYFIP1 involved in several pathways and played different roles in them. We selected most pathways CYFIP1 participated on our site, such as RNA transport, Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYFIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA transport	SRRM1;FXR2;EIF2B4;RANGAP1A;EIF2S2;NCBP2;GEMIN4;EIF4A3;GEMIN8
Regulation of actin cytoskeleton	RHOAB;PIP5KL1;ITGAE;ARAF;PTK2AA;F2;RHOAC;INSRR;PXN

CYFIP1 has several biochemical functions, for example, contributes_to Rac GTPase binding, actin binding, profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYFIP1 itself. We selected most functions CYFIP1 had, and list some proteins which have the same functions with CYFIP1. You can find most of the proteins on our site.

Function	Related Protein
contributes_to Rac GTPase binding	BRK1;NCKAP1;WASF1;CYFIP1;ABI2
actin binding	MYH1;TNS1;ACTN3B;CNN1;CORO7;SCIN;WASF3;SSH2B;INF2
profilin binding	DIAP1;HTT;DIAPH1;PCLO;RHOQ;FMNL1;WIPF1;CTTN;CYFIP1
protein binding	TP53;ZFP64;ADAMTS4;TMPRSS2;MLLT3;PRAC;ANK1;GDNF;ATXN3
protein complex binding	HNF1B;STK11;PFKP;MLC1;RNF40;C8B;NASP;TG;PTK2B

CYFIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYFIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYFIP1.

Eif4e; Fmr1; map1b_mouse_mrna; Pik3r1; Eif6; Rps6; FMR1; 7-methyl-gtp

Abekhoukh, S; Bardoni, B; et al. CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome. FRONTIERS IN CELLULAR NEUROSCIENCE 8:-(2014).

Bozdagi, O; Sakurai, T; et al. Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice. PLOS ONE 7:-(2012).