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CYGB

  • Official Full Name

    cytoglobin

  • Overview

    This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate;hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may;be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a;retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.
  • Synonyms

    CYGB; cytoglobin; HGB; histoglobin; STAP; stellate cell activation associated protein; stellate cell activation-associated protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • SUMO
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CYGB-7803H Recombinant Human CYGB E.coli N/A
Human CYGB-2578H Recombinant Human Cytoglobin, His-tagged E.coli His
Human CYGB-371H Recombinant Human CYGB protein, His-tagged E.coli His Met1-Pro190
Human CYGB-2231H Recombinant Human CYGB Protein, GST-tagged Wheat Germ GST
Human CYGB-26694TH Recombinant Human CYGB, His-tagged E.coli His 190 amino acids
Human CYGB-7134HCL Recombinant Human CYGB 293 Cell Lysate HEK293 N/A
Human CYGB-2783H Recombinant Human CYGB protein, His-SUMO-tagged E.coli His-SUMO 1-190aa
Human CYGB-669H Recombinant Human CYGB Protein, His-tagged E.coli His Met1~Pro190
Human CYGB-1731H Recombinant Human CYGB Protein (Met1-Pro190), C-His tagged E.coli C-His Met1-Pro190
Human CYGB-2271HF Recombinant Full Length Human CYGB Protein, GST-tagged In Vitro Cell Free System GST 190 amino acids
Mouse Cygb-535M Recombinant Mouse Cygb Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CYGB-1711R Recombinant Rat CYGB Protein Mammalian Cell His
Rat CYGB-1370R Recombinant Rat CYGB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cygb-670R Recombinant Rat Cygb Protein, His-tagged E.coli His Met1~Pro190
Rat Cygb-2784R Recombinant Rat Cygb protein, His&Myc-tagged E.coli His&Myc 1-190aa
Rat CYGB-1370R-B Recombinant Rat CYGB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CYGB-1132R Recombinant Rhesus monkey CYGB Protein, His-tagged Mammalian Cell His
Rhesus Macaque CYGB-957R-B Recombinant Rhesus Macaque CYGB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CYGB-957R Recombinant Rhesus Macaque CYGB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CYGB-1874C Recombinant Chicken CYGB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CYGB Related Articles

CYGB involved in several pathways and played different roles in them. We selected most pathways CYGB participated on our site, such as Metabolism, Metabolism of nitric oxide, eNOS activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYGB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MetabolismPDK3B;SLC25A1A;SLC6A12;ACAD11;GCHFR;LMF2;DGAT1B;COX11;AGL
Metabolism of nitric oxideCYGB1;CYGB2;ZDHHC21;SPRB;DDAH1;NOSTRIN;DDAH2;LYPLA1;CYGB
eNOS activationCYGB2;DDAH1;LYPLA1;ZDHHC21;CYGB;DDAH2;CYGB1
eNOS activation and regulationZDHHC21;DDAH1;CYGB2;GCHFR;SPRB;DDAH2;CYGB;NOSTRIN;NOSIP

CYGB has several biochemical functions, for example, catalase activity, fatty acid peroxidase activity, heme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYGB itself. We selected most functions CYGB had, and list some proteins which have the same functions with CYGB. You can find most of the proteins on our site.

Function Related Protein
catalase activityCAT;CYGB;GPX7
fatty acid peroxidase activity
heme bindingCYP3A25;CYP2A6;CYP4F12;CYP2A4;CYP3A7;IDO2;CYP3A4;CYP27A1;CYP1A4
iron ion bindingCYP4V8;CYP2P10;FAXDC2;NOS2A;CYP11B2;CYP2C70;CYP2A6;ETHE1;CYP2AA6
nitric oxide dioxygenase activityCYGB;POR
oxygen bindingHBB-BH1;CYP2R1;CYP2J6;CYP2AA8;TDO2;CYP2AA12;TH;CYP2A4;HBG1
oxygen transporter activityHBA2;XGB;HBAA1;HBAE3;HBM;HBD;HBBE1.1;CYGB2;NGB
peroxidase activityGPX8;PRDX1;PTGS2B;GPX4B;MGST3;PTGS2A;GPX6;MPX;GPX5
protein bindingPYGM;NOG;ARPM1;SYT7;SATB1;TTC19;STX16;EDNRB;DDX18

CYGB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYGB here. Most of them are supplied by our site. Hope this information will be useful for your research of CYGB.

DDI1; ATP13A2

Fujita, Y; Koinuma, S; et al. Melanoma Transition Is Frequently Accompanied by a Loss of Cytoglobin Expression in Melanocytes: A Novel Expression Site of Cytoglobin. PLOS ONE 9:-(2014).
Motoyama, H; Komiya, T; et al. Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver. LABORATORY INVESTIGATION 94:192-207(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does CYGB protein contribute to the regulation of cellular metabolism? 08/20/2021

CYGB has been implicated in the modulation of cellular metabolism, particularly in the context of oxygen sensing and energy metabolism.

Can CYGB protein be used as a biomarker for cancer diagnosis? 01/05/2020

Research indicates that CYGB expression levels may serve as a potential biomarker for cancer diagnosis and prognosis.

How is CYGB protein related to neurodegenerative diseases such as Alzheimer's and Parkinson's? 08/11/2018

Studies have suggested that CYGB may play a role in protecting neurons from oxidative stress, making it a potential target for neurodegenerative disease treatment.

Can CYGB protein be used as a therapeutic target for cardiovascular diseases? 09/22/2017

Research has explored the potential of targeting CYGB for the treatment of cardiovascular diseases, including myocardial infarction and heart failure.

What are the potential therapeutic applications of CYGB protein in cancer treatment? 08/07/2016

CYGB has been investigated as a potential target for cancer therapy due to its involvement in apoptosis and tumor suppression.

Customer Reviews (3)

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Reviews
08/25/2021

    This guarantees that the protein is reliable, consistent, and suitable for experiments, reducing variability and enhancing the reproducibility of findings.

    02/04/2019

      The manufacturer can offer technical support and expertise to guide researchers through the experimental process.

      09/21/2017

        the manufacturer can play a vital role in supporting and optimizing the research process.

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