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CYP26C1

Official Full Name

cytochrome P450, family 26, subfamily C, polypeptide 1
Overview

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33.
Synonyms

CYP26C1; cytochrome P450, family 26, subfamily C, polypeptide 1; cytochrome P450 26C1; FLJ45301;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	CYP26C1-2252H	Recombinant Human CYP26C1 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	CYP26C1-3391H	Recombinant Human CYP26C1 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Human	CYP26C1-2679H	Recombinant Human CYP26C1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	Cyp26c1-2416M	Recombinant Mouse Cyp26c1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Zebrafish	CYP26C1-3181Z	Recombinant Zebrafish CYP26C1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

CYP26C1 involved in several pathways and played different roles in them. We selected most pathways CYP26C1 participated on our site, such as Retinol metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP26C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Retinol metabolism	UGT1A6B;HSD17B6;UGT2A1;RDH10;SDR16C5A;RDH8;DHRS4L2;ALDH1A2;CYP3A41B
Metabolic pathways	STT3A;GRHPRA;GALC;NMNAT2;DNMT3;B3GALT6;HADHAB;ACO1;TBXAS1

CYP26C1 has several biochemical functions, for example, heme binding, iron ion binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP26C1 itself. We selected most functions CYP26C1 had, and list some proteins which have the same functions with CYP26C1. You can find most of the proteins on our site.

Function	Related Protein
heme binding	CYP2E1;EIF2AK1;CYP27C1;IRGM1;NOX4;CYP51;CYP2Y3;CYP2R1;CYP4F22
iron ion binding	CYP2J5;OGFOD3;CYP2A6;CYP1A;CYP21A1;CYP2C55;ISCUB;CYP4V2;CYP2AA9
metal ion binding	STK25;ZFYVE9;HBAA1;TIMM10B;RPS27.2;ZSWIM4;ZNF230;CRYABA;DNAJA2
monooxygenase activity	CYP4T8;CYP7A1A;COQ6;FOXRED2;CYP8B2;CYP3A25;CYP2V1;CYP2X9;CYP2AD3
oxidoreductase activity	HSD17B12B;RNLS;CYP2C39;CYBASC3;TYRP1B;SDR16C5A;EGLN1B;SCCPDH;ETFA
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	CYP2K19;P4HA1A;CYP2C70;CYP2F2;CYP2D26;CYP2AA7;CYP2K18;CYP2AD2;CYP19A1A

CYP26C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP26C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP26C1.