Cacul1
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Official Full Name
CDK2-associated, cullin domain 1
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Rat
- Rhesus Macaque
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | CACUL1-1686HF | Recombinant Full Length Human CACUL1 Protein, GST-tagged | In Vitro Cell Free System | GST | 303 amino acids | |
Rat | CACUL1-1078R | Recombinant Rat CACUL1 Protein | Mammalian Cell | His | ||
Rat | CACUL1-742R-B | Recombinant Rat CACUL1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | CACUL1-742R | Recombinant Rat CACUL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | CACUL1-605R | Recombinant Rhesus monkey CACUL1 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | CACUL1-433R-B | Recombinant Rhesus Macaque CACUL1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | CACUL1-433R | Recombinant Rhesus Macaque CACUL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
Cacul1 involved in several pathways and played different roles in them. We selected most pathways Cacul1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Cacul1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cacul1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Cacul1 itself. We selected most functions Cacul1 had, and list some proteins which have the same functions with Cacul1. You can find most of the proteins on our site.
Function | Related Protein |
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Cacul1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cacul1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cacul1.
- Q&As
- Reviews
Q&As (5)
Ask a questionCACUL1's subcellular localization varies throughout the cell cycle. It shuttles between the nucleus and cytoplasm, and this dynamic localization is essential for its role in cell cycle regulation and DNA damage response.
CACUL1 promotes cell cycle progression by forming complexes with CDKs and Cyclins, facilitating their activation. This leads to the phosphorylation of target proteins that drive the cell cycle forward.
CACUL1 interacts with several key cell cycle regulators, including Cyclin-Dependent Kinases (CDKs) and Cyclins. It also interacts with proteins involved in DNA damage repair and checkpoint control.
Emerging research suggests that CACUL1 is involved in epigenetic regulation by influencing chromatin remodeling processes. It can interact with histone modifiers and transcription factors, leading to changes in gene expression profiles in cancer cells. Understanding these epigenetic mechanisms is vital for targeted cancer therapies.
CACUL1 expression is tightly regulated at the transcriptional level. It is upregulated in many cancer types due to aberrant transcriptional activation, which can be driven by various oncogenic pathways.
Customer Reviews (3)
Write a reviewProduct exceeded my expectations!
Easy to use and effective.
Great value for the price.
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