CALCR
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Official Full Name
calcitonin receptor
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Overview
receptor for calcitonin; acts via adenylate cyclase signaling [RGD, Feb 2006] -
Synonyms
CALCR; calcitonin receptor; CT-R; C1A/C1B;
- Recombinant Proteins
- Cell & Tissue Lysates
- Assay Kits
- Cavia porcellus (Guinea pig)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Oryctolagus cuniculus (Rabbit)
- Rat
- Rattus norvegicus (Rat)
- Sus scrofa (Pig)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Wheat Germ
- Fc
- GST
- His
- Flag
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CALCR-27793TH | Recombinant Human CALCR | Wheat Germ | N/A | 81 amino acids |
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| Human | CALCR-742H | Recombinant Human CALCR Protein, Fc-tagged | HEK293 | Fc |
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| Human | CALCR-0296H | Recombinant Human CALCR Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CALCR-743H | Recombinant Human CALCR Protein, Fc-tagged | HEK293 | Fc |
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| Human | CALCR-272HCL | Recombinant Human CALCR cell lysate | N/A |
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| Human | CALCR-1054HFL | Recombinant Human CALCR protein, His&Flag-tagged | HEK293 | His&Flag | 1-490 aa |
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| Human | CALCR-3051HF | Recombinant Full Length Human CALCR Protein, GST-tagged | In Vitro Cell Free System | GST | 474 amino acids |
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| Mouse | Calcr-649M | Recombinant Mouse Calcr Protein, His-tagged | E.coli | His | Ala42~Leu170 |
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| Rat | Calcr-650R | Recombinant Rat Calcr Protein, His-tagged | E.coli | His | Val34~Tyr148 |
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| Cavia porcellus (Guinea pig) | RFL14648CF | Recombinant Full Length Guinea Pig Calcitonin Receptor(Calcr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (23-478) |
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| Homo sapiens (Human) | RFL24997HF | Recombinant Full Length Human Calcitonin Receptor(Calcr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (25-490) |
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| Mus musculus (Mouse) | RFL25734MF | Recombinant Full Length Mouse Calcitonin Receptor(Calcr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (25-515) |
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| Oryctolagus cuniculus (Rabbit) | RFL27826OF | Recombinant Full Length Rabbit Calcitonin Receptor(Calcr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (23-474) |
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| Rattus norvegicus (Rat) | RFL24242RF | Recombinant Full Length Rat Calcitonin Receptor(Calcr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (25-516) |
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| Sus scrofa (Pig) | RFL21043SF | Recombinant Full Length Pig Calcitonin Receptor(Calcr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (30-498) |
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| Kit-0974 | TR-FRET PPAR alpha Coactivator Assay Kit, goat | N/A |
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| Kit-1136 | CALCR CHO-K1 β-Arrestin GPCR Assay Kit | N/A |
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| Kit-0975 | TR-FRET ERR alpha Coactivator Assay Kit, goat | N/A |
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| Kit-1137 | CALCR U2OS β-Arrestin GPCR Assay Kit | N/A |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CALCR Related Articles
- CALCR Related Gene Family
- CALCR Related Research Area
CALCR involved in several pathways and played different roles in them. We selected most pathways CALCR participated on our site, such as Neuroactive ligand-receptor interaction, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CALCR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | TAAR1B;HCRTR2;P2RY4;DRD2L;GABRA2;FPR3;PRP2;PPYR1;TACR3A |
| Osteoclast differentiation | ITGB3;CSF1;LILRA3;AKT1;LILRB3;TGFB1;TNFRSF1A;MAPK10;FYN |
CALCR has several biochemical functions, for example, calcitonin binding, NOT calcitonin binding, calcitonin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CALCR itself. We selected most functions CALCR had, and list some proteins which have the same functions with CALCR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcitonin binding | |
| NOT calcitonin binding | |
| calcitonin receptor activity | CALCRL;RAMP1;CALCRLA;CALCR |
| protein binding | Itga10&Itgb1;C5orf30;CPSF3;CFTR;TDO2;ALDOB;CD93;PKN2;GRAP |
| protein transporter activity | TIMM9;SEC61G;VPS26BL;FRAG1;IPO5;C11orf73;KPNA6;KPNB3;VPS26A |
| receptor activity | GFRA4A;GRIA4B;THBD;RTN4RL2;MRC1;FKBP3;CD160;LRP2;TLR4 |
CALCR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALCR here. Most of them are supplied by our site. Hope this information will be useful for your research of CALCR.
GPRASP1; GPRASP2; CALM1
- Q&As
- Reviews
Q&As (5)
Ask a questionCALCR is expressed in MTC cells. Measuring CALCR expression can serve as a diagnostic marker for MTC, helping to identify and diagnose this type of thyroid cancer.
The CALCR receptor is the target for calcitonin. When calcitonin binds to CALCR on osteoclasts, it inhibits bone resorption, helping to maintain bone health.
CALCR is specific to calcitonin signaling. Downstream signaling pathways include activation of G proteins, which affect intracellular calcium levels and other signaling molecules.
CALCR activation in osteoclasts inhibits bone resorption, which plays a crucial role in maintaining calcium homeostasis by reducing calcium release from bone.
CALCR activation by calcitonin has been used in the treatment of osteoporosis to inhibit bone resorption, thus helping to maintain bone density.
Customer Reviews (3)
Write a reviewIt's clear that the product is meticulously crafted for laboratory use.
My experiments rely on the consistency of the product, and it hasn't let me down.
The product exceeded my expectations in terms of quality and performance.
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