CANX
-
Official Full Name
calnexin
-
Overview
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. -
Synonyms
CANX; calnexin; CNX; P90; IP90; major histocompatibility complex class I antigen-binding protein p88;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Canis lupus familiaris (Dog) (Canis familiaris)
- Chicken
- Dog
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E. coli
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- hFc
- His
- Flag
- GST
- His (Fc)
- Avi
- His|GST
- His|MBP
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CANX Related Articles
CANX involved in several pathways and played different roles in them. We selected most pathways CANX participated on our site, such as Protein processing in endoplasmic reticulum, Phagosome, Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CANX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | DNAJB12;XBP1;CALR3B;VCP;TRAF2;DNAJC10;UGGT1;FBXO6;HSP90AA1 |
| Phagosome | COLEC12;ATP6V1BA;THBS4;ATP6V1E1B;M6PR;SEC22BA;HLA-DRB5;ATP6V0C;FCGR2A |
| Antigen processing and presentation | CD74;KIR2DS4;KIR2DL1;TAP2;KLRD1;HLA-B;Ctsl;HLA-DOB;CD8A |
| Thyroid hormone synthesis | PDIA4;ATF4;Adcy4;PRKCG;FXYD2;CANX;GPX8;ATP1B1;PLCB1 |
| HTLV-I infection | NFKB1;ANAPC7;ANAPC1;KAT2A;MYB;HLA-DQA1;SLC25A6;TRP53INP1;POLB |
CANX has several biochemical functions, for example, apolipoprotein binding, calcium ion binding, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CANX itself. We selected most functions CANX had, and list some proteins which have the same functions with CANX. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| apolipoprotein binding | MAPT;VLDLR;ABCA1;LPA;LRP6;CANX;PLG;SCARB1;LRP1 |
| calcium ion binding | PRF1;CABP2A;PLA2G1B;SVEP1;PCDHA10;MYL1;MMP14B;FLG2;CMLC1 |
| carbohydrate binding | ITLN1;REG3A;ILLR1;NOMO3;FCNA;FCN1;CLEC4D;SIGLEC12;CD207 |
| glycoprotein binding | SDCBP;SELP;VWF;AZGP1;FGFR1;RGMA;LDLR;LGALS1;VIM |
| ionotropic glutamate receptor binding | DLG1;DLG4;DLG1L;DRD2;SHANK3;SHANK1;DLG2;DLG4B;DLG3 |
| poly(A) RNA binding | PRPF4B;RPS27.1;RBM7;MRPL15;EIF2S2;HSPD1;REPIN1;NOP14;MRPS5 |
| protein binding | KPNA1;HBA2;UBL4A;CRIPT;NLRP1;IL18R1;ADA;RIN1;ZNF580 |
| unfolded protein binding | HSPA1A;CHAF1B;CRYAA;DNAJA2;SIL1;DNAJB6;RP2;CANX;ST13 |
CANX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CANX here. Most of them are supplied by our site. Hope this information will be useful for your research of CANX.
CFTR; SSR1; Tor1aip1; ATP2A2; ATP2A2; OPRD1; env; RPL12
- Q&As
- Reviews
Ask a Question for All CANX Products
Required fields are marked with *
My Review for All CANX Products
Required fields are marked with *
