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CBLB

  • Official Full Name

    Cbl proto-oncogene, E3 ubiquitin protein ligase B

  • Overview

    E3 ubiquitin-protein ligase CBL-B is an enzyme that in humans is encoded by the CBLB gene.
  • Synonyms

    CBLB; Cbl proto-oncogene, E3 ubiquitin protein ligase B; Cas Br M (murine) ecotropic retroviral transforming sequence b , Cas Br M (murine) ectropic retroviral transforming sequence b; E3 ubiquitin-protein ligase CBL-B; Cbl b; RNF56; RING finger protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect cells
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CBLB-579H Recombinant Human CBLB, GST-tagged Wheat Germ GST
Human CBLB-578H Recombinant Human CBLB, GST-tagged Wheat Germ GST
Human CBLB-10756H Recombinant Human CBLB, His-tagged E.coli His N-term-352a.a.
Human CBLB-18H Recombinant Human CBLB, MYC/DDK-tagged HEK293 Myc/DDK
Human CBLB-7814HCL Recombinant Human CBLB 293 Cell Lysate HEK293 N/A
Human CBLB-036H Recombinant Human CBLB Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human CBLB-558HF Recombinant Full Length Human CBLB Protein, GST-tagged In Vitro Cell Free System GST 982 amino acids
Human CBLB-733H Recombinant Human CBLB protein, His-tagged E.coli His Ala39-Phe426
Human CBLB-19H Recombinant Human CBLB Protein, His-Avi-tagged, Biotinylated E.coli His/Avi
Human CBLB-301611H Recombinant Human CBLB protein, GST-tagged E.coli GST Met1-His352
Human CBLB-01H Active Recombinant Human CBLB Protein Insect cells
Human CBLB-3615HFL Recombinant Full Length Human CBLB, Flag-tagged Mamanlian cells Flag
Mouse Cblb-1974M Recombinant Mouse Cblb Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat CBLB-1155R Recombinant Rat CBLB Protein Mammalian Cell His
Rat CBLB-813R-B Recombinant Rat CBLB Protein Pre-coupled Magnetic Beads HEK293
Rat CBLB-813R Recombinant Rat CBLB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CBLB involved in several pathways and played different roles in them. We selected most pathways CBLB participated on our site, such as ErbB signaling pathway, Ubiquitin mediated proteolysis, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBLB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayPRKCA;PAK6B;CAMK2D1;NCK2A;STAT5A;TGFA;CDKN1BA;RPS6KB1;PAK2
Ubiquitin mediated proteolysisSIAH1A;CDC34A;NEDD4L;VHL;FBXW7;SYVN1;SOCS1;FBXW11B;UBE2E2
EndocytosisEHD1;WIPF2B;H2-Q10;VPS26BL;HLA-B;CAV3;DNM3;HSC70;WASB
T cell receptor signaling pathwayZAP70;IL5;FOS;PAK2;CD8A;PIK3R3;ICOS;MAPK13;NFKBIA
Insulin signaling pathwayPYGMA;KRAS;PTPRFB;SOCS1A;PRKACAA;PDE3B;RAPGEF1B;TRIP10;ACACB
Bacterial invasion of epithelial cellsSEPT1;PIK3R5;PIK3R2;WASF1;CAV1;CTNNA1;CRK;PIK3CG;ARPC3
MeaslesTLR7;IFNA16;MSN;IFNAR1;HSPA1A;IFNGR2;IRAK4;STAT5B;IL6
Pathways in cancerWNT1;ARHGEF12;CSF1R;GNGT2;LAMA1;HGF;RXRG;RASSF5;PPARG
Proteoglycans in cancerWNT2B;MAP2K2;TWIST1;BRAF;ANK1;MAPK11;WNT8A;CBLB;PTPN6
Chronic myeloid leukemiaRB1;MAP2K2;HDAC2;PIK3R1;ARAF;PIK3CD;PIK3R2;HRAS;NFKB1

CBLB has several biochemical functions, for example, calcium ion binding, ligase activity, phosphotyrosine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBLB itself. We selected most functions CBLB had, and list some proteins which have the same functions with CBLB. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingEMR4;PCDH1G30;CETN4;SNCA;OCM;CAPN12;ARSA;DGKA;S100A5
ligase activityRNF20;BRCA1;ATG3;RNF19A;FPGS;RAD18;NEURL1B;TRIM56;MARCH3
phosphotyrosine bindingLDLRAP1;CBLC;STAP1;FGR;PTPN3;CBL;CBLB;ACP2;MAPK3
protein bindingSET;IGSF8;MTPAP;JUN;CD47;CARKD;CAND2;RTN1;CD22
signal transducer activityMRGPRB5;OLFR78;OMP;OLFCD2;CXCR4B;SLC44A2;CANT1;MUL1;OLFR149
ubiquitin-protein transferase activityUBE2L3;TRIM23;SKP1;TRAF2;UBE2D4;LMO7;RCHY1;ZNRF1;FBXW11
zinc ion bindingZCWPW2;EEA1;NHLRC1;ALPP;LNX2B;ZDHHC7;MMP14A;LMO4A;PDZRN3

CBLB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBLB here. Most of them are supplied by our site. Hope this information will be useful for your research of CBLB.

SH3KBP1

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