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CCT8

  • Official Full Name

    chaperonin containing TCP1, subunit 8 (theta)

  • Overview

    T-complex protein 1 subunit theta is a protein that in humans is encoded by the CCT8 gene.
  • Synonyms

    CCT8; chaperonin containing TCP1, subunit 8 (theta); C21orf112, chromosome 21 open reading frame 112; T-complex protein 1 subunit theta; Cctq; PRED71; C21orf112; CCT 8; CCT theta; Chaperonin containing TCP1 subunit 8 (theta); Chaperonin subunit 8 (Theta) (Predicted), isoform CRA_a; Chaperonin subunit 8 (theta); Chromosome 21 open reading frame 112; D21S246; KIAA0002; Renal carcinoma antigen NY REN 15; T complex protein 1 subunit theta; T complex protein 1 theta subunit; TCP 1 theta; Tcpq; CCT-theta; TCP-1-theta; renal carcinoma antigen NY-REN-15; T-complex protein 1, theta subunit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCT8-10901H Recombinant Human CCT8, GST-tagged E.coli GST C-term-350a.a.
Human CCT8-0719H Recombinant Human CCT8 Protein, GST-Tagged Wheat Germ GST
Human CCT8-7686HCL Recombinant Human CCT8 293 Cell Lysate HEK293 N/A
Human CCT8-336H Recombinant Human CCT8 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human CCT8-2942HF Recombinant Full Length Human CCT8 Protein, GST-tagged In Vitro Cell Free System GST 27 amino acids
Mouse CCT8-3030M Recombinant Mouse CCT8 Protein Mammalian Cell His
Mouse CCT8-1432M-B Recombinant Mouse CCT8 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cct8-809M Recombinant Mouse Cct8 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CCT8-1432M Recombinant Mouse CCT8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CCT8-384C Recombinant Cynomolgus CCT8 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CCT8-132C Recombinant Cynomolgus Monkey CCT8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CCT8-132C-B Recombinant Cynomolgus Monkey CCT8 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CCT8-716R Recombinant Rhesus monkey CCT8 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCT8-543R Recombinant Rhesus Macaque CCT8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CCT8-543R-B Recombinant Rhesus Macaque CCT8 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CCT8-11289Z Recombinant Zebrafish CCT8 Mammalian Cell His
Chicken CCT8-1208C Recombinant Chicken CCT8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CCT8 involved in several pathways and played different roles in them. We selected most pathways CCT8 participated on our site, such as Assembly of the primary cilium, Association of TriC/CCT with target proteins during biosynthesis, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCT8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Assembly of the primary ciliumCEP89;CEP76;TTC30A2;BBS5;EXOC1;NINL;CCP110;CCT3;MAPRE1A
Association of TriC/CCT with target proteins during biosynthesisFBXW2;FBXW5;CCT3;NOP56;CCT6A;CCT4;FBXL5;CCT2;CCT8
BBSome-mediated cargo-targeting to ciliumBBS10;TCP1;LZTFL1;BBS4;BBS9;BBS1;BBS7;MKKS;SSTR3
Cargo trafficking to the periciliary membraneARF4A;BBS4;UNC119B;EXOC8;BBS5;CNGA5;EXOC5;ARF4;BBS1
Chaperonin-mediated protein foldingPFDN4;TUBA1B;PFDN5;VBP1;FKBP9;CCT7;CCT4;FBXW4;PFDN6
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingCCT3;TUBA3D;PFDN6;CCT8;CCT7;TUBB4B;VBP1;PFDN2;TUBB4A
Folding of actin by CCT/TriCCCT3;CCT7;CCT4;CCT8;TCP1;CCT2;CCT5;CCT6A
Formation of tubulin folding intermediates by CCT/TriCCCT2;TUBA1B;CCT3;CCT5;CCT7;TUBB4B;TUBB4A;CCT8;TCP1

CCT8 has several biochemical functions, for example, ATP binding, ATPase activity, coupled, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCT8 itself. We selected most functions CCT8 had, and list some proteins which have the same functions with CCT8. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSTK17A;ERCC6L2;GTF2F2A;ABCF3;NME2;ACVRL1;NWD1;HSP90AA1.1;NLRP7
ATPase activity, coupledMYH3;HSPA1B;HSP104;ABCB1A;HSPA6;VPS4B;HSPA1A;HSPA8;VPS4A
protein bindingPHB2;CNNM3;PRPF8;NUBP2;MPDU1;RND2;TGFBR1;ATF6;XRCC1
unfolded protein bindingHTRA2;CHAF1B;HSPA5;AHSP;AIP;CLN3;TRAP1;NPM1;DNAJA2

CCT8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCT8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCT8.

PPP4C; PPP2CB; PPP2CA; STRN3; ILK; STRN; JAK3; IGBP1

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